ADVERSE REACTION FOLLOWING INTRAVENOUS IMMUNOGLOBULIN IN PRIMARY IMMUNODEFICIENCY PATIENTS

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GHAFARI JAVAD; GHARAHGOUZLOU MOHAMMAD; MOHAMMADZADEH I.; NAZARI ZEYNAB

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Journal: Journal of Mazandaran University of Medical Sciences Year:2008 | Volume:17 | Issue:61 Page(s): 114-121

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Information Journal Paper

Title

ADVERSE REACTION FOLLOWING INTRAVENOUS IMMUNOGLOBULIN IN PRIMARY IMMUNODEFICIENCY PATIENTS

Author(s)

GHAFARI JAVAD | GHARAHGOUZLOU MOHAMMAD | MOHAMMADZADEH I. | NAZARI ZEYNAB | Issue Writer Certificate

Keywords

INTRAVENOUS IMMUNOGLOBULINQ3

PRIMARY IMMUNODEFICIENCYQ2

SIDE EFFECTSQ3

Abstract

Background and Purpose: INTRAVENOUS IMMUNOGLOBULIN is used for PRIMARY IMMUNODEFICIENCY disorders. There have been some reports that INTRAVENOUS IMMUNOGLOBULIN causes SIDE EFFECTS. The aim of this study was to investigate INTRAVENOUS IMMUNOGLOBULIN SIDE EFFECTS in immunodeficiency patients.Materials and Methods: The study utilized the data of 29 PRIMARY IMMUNODEFICIENCY patients that were referred to allergy and immunology department in Medical Children Center in Tehran. 29 patients having completed record data files in the hospital were the subjects of this study.Results: Of 29 immune deficiency patients (aged 15 months to 55 years), they were 19 Males (65/51%) and 10(34/48%) Females Prevalence of disorders include common variable immunodeficiency 16(55/17%), Bruton disease 8(27/58%), hyper IgM 4 (13/79%) and severe combined immunodeficiency (3/44%). Based on the recorded data, the duration of infusion has been 5 months to 15 years. 15 patients had reported SIDE EFFECTS (51/72%). 34 infusions from the total of 1,626 infusions accompanied with SIDE EFFECTS (2/09%) Most SIDE EFFECTS were occurred during 30 minutes onset of infusion and most were caused by rapid infusion. Most SIDE EFFECTS were mild reactions (fever, chills and ...). Conclusion: INTRAVENOUS IMMUNOGLOBULIN is a rather safe drug with mild SIDE EFFECTS. With an appropriate technique and proper infusion, these SIDE EFFECTS can be reduced.

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APA: Copy

GHAFARI, JAVAD, GHARAHGOUZLOU, MOHAMMAD, MOHAMMADZADEH, I., & NAZARI, ZEYNAB. (2008). ADVERSE REACTION FOLLOWING INTRAVENOUS IMMUNOGLOBULIN IN PRIMARY IMMUNODEFICIENCY PATIENTS . JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 17(61), 114-121. SID. https://sid.ir/paper/45909/en

Vancouver: Copy

GHAFARI JAVAD, GHARAHGOUZLOU MOHAMMAD, MOHAMMADZADEH I., NAZARI ZEYNAB. ADVERSE REACTION FOLLOWING INTRAVENOUS IMMUNOGLOBULIN IN PRIMARY IMMUNODEFICIENCY PATIENTS . JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;17(61):114-121. Available from: https://sid.ir/paper/45909/en

IEEE: Copy

JAVAD GHAFARI, MOHAMMAD GHARAHGOUZLOU, I. MOHAMMADZADEH, and ZEYNAB NAZARI, “ADVERSE REACTION FOLLOWING INTRAVENOUS IMMUNOGLOBULIN IN PRIMARY IMMUNODEFICIENCY PATIENTS ,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 61, pp. 114–121, 2008, [Online]. Available: https://sid.ir/paper/45909/en

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