PREVALENCE OF MRSA AND VRSA STRAINS OF STAPHYLOCOCCUS AUREUS IN HEALTHCARE STAFF AND INPATIENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FIROUZI FATEMEH; AKHTARI JAVAD; NASROLAHEI MOHTARAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download Full-Text

Persian Verion

View:

1,261

Download:

Cites:

Information Journal Paper

Title

PREVALENCE OF MRSA AND VRSA STRAINS OF STAPHYLOCOCCUS AUREUS IN HEALTHCARE STAFF AND INPATIENTS

Author(s)

FIROUZI FATEMEH | AKHTARI JAVAD | NASROLAHEI MOHTARAM | Issue Writer Certificate

Keywords

NOSOCOMIAL INFECTIONQ3

POLYMERASE CHAIN REACTIONQ2

MAZANDARANQ2

METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUSQ2

VANCOMYCIN-RESISTANT STAPHYLOCOCCUS AUREUSQ1

Abstract

Background and purpose: Methicillin-resistant Staphylococcus. aureus (MRSA) is specific strain of S.aureus that is a major cause of NOSOCOMIAL INFECTION. Nowadays, Vancomycin is the first-line treatment of severe MRSA infections. However, resistance to Vancomycin is reported in the form of VANCOMYCIN-RESISTANT STAPHYLOCOCCUS AUREUS (VRSA) too. This study aimed at determining the prevalence of MRSA and VRSA in healthcare staff and inpatients.Materials and methods: The study was performed in 447 healthcare workers and inpatients in Teaching Hospitals, in Sari, Iran, 2015. Staphylococcus aureus were isolated from the subjects using diagnostic tests. Then antibiotic resistance patterns of the isolates was determined by disk diffusion method.E-TEST was used for the methicillin and Vancomycin resistant isolates. Prevalence of mecA resistant gene in the isolates was analyzed by PCR. Finally, Induced resistance to Clindamycin was investigated.Results: E-TEST showed that 31.31% of the isolates were resistant to methicillin and 16.1% were vancomycin-intermediate S. aureus (VISA). Prevalence of mecA gene in resistant isolates was 96.8%. The highest resistance was detected against Gentamicin (45.5%) and the lowest resistance rates were found against Vancomycin (0%) and Amikacin (14.1%). We also found that 12.9% of MRSA isolates were inducible resistance to Clindamycin.Conclusion: This study revealed that MRSA isolates have a high resistance to Erythromycin, Clindamycin, Gentamicin, and Ciprofloxacin. Also, a high rate of multidrug-resistant was seen in MRSA isolates. But despite intermediate resistance to Vancomycin, this antibiotic can be used as a valuable drug in treatment of MRSA.

Cites

No record.

References

No record.

Cite

APA: Copy

FIROUZI, FATEMEH, AKHTARI, JAVAD, & NASROLAHEI, MOHTARAM. (2016). PREVALENCE OF MRSA AND VRSA STRAINS OF STAPHYLOCOCCUS AUREUS IN HEALTHCARE STAFF AND INPATIENTS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 26(142), 96-107. SID. https://sid.ir/paper/45927/en

Vancouver: Copy

FIROUZI FATEMEH, AKHTARI JAVAD, NASROLAHEI MOHTARAM. PREVALENCE OF MRSA AND VRSA STRAINS OF STAPHYLOCOCCUS AUREUS IN HEALTHCARE STAFF AND INPATIENTS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;26(142):96-107. Available from: https://sid.ir/paper/45927/en

IEEE: Copy

FATEMEH FIROUZI, JAVAD AKHTARI, and MOHTARAM NASROLAHEI, “PREVALENCE OF MRSA AND VRSA STRAINS OF STAPHYLOCOCCUS AUREUS IN HEALTHCARE STAFF AND INPATIENTS,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 142, pp. 96–107, 2016, [Online]. Available: https://sid.ir/paper/45927/en

Related Journal Papers