THE SURVEY OF ANTI-INFLAMMATORY EFFECT OF BISPHOSPHONATES

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SHIARI R.; NASEHI M.M.; FARIVAR SH.; HATAMIAN BIZHAN

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Journal Paper

Paper Information

Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2009 | Volume:19 | Issue:69 Page(s): 79-87

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Title

THE SURVEY OF ANTI-INFLAMMATORY EFFECT OF BISPHOSPHONATES

Author(s)

SHIARI R. | NASEHI M.M. | FARIVAR SH. | HATAMIAN BIZHAN | Issue Writer Certificate

Keywords

BIPHOSPHONATEQ2

ANTI-INFLAMMATORYQ3

CYTOKINEQ3

Abstract

Bisphosphonates are currently used in metabolic disorder of bone; however, there have been few studies that reviewed the role of ANTI-INFLAMMATORY and immune modulatory effect of this agent in in-vivo. Bisphosphonates were divided in two classes regarding the structure and mechanism, including amino and non-amino bisphosphonates. The effect of bisphosphonates on CYTOKINE related to in-vitro was complex and related to type and dose of bisphosphonates, examination of cell type and cell culture evaluation system. However, amino bisphosphonates activated inflammatory CYTOKINE regarding to in-vivo and chronic usage of this agent, can stop the production of these CYTOKINEs. Present study surveyed the anti -inflammatory and immune modulatory effect of bisphosphonates and clinical trial, along with recent knowledge about potential mechanism of this component.

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APA: Copy

SHIARI, R., NASEHI, M.M., FARIVAR, SH., & HATAMIAN, BIZHAN. (2009). THE SURVEY OF ANTI-INFLAMMATORY EFFECT OF BISPHOSPHONATES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 19(69), 79-87. SID. https://sid.ir/paper/46131/en

Vancouver: Copy

SHIARI R., NASEHI M.M., FARIVAR SH., HATAMIAN BIZHAN. THE SURVEY OF ANTI-INFLAMMATORY EFFECT OF BISPHOSPHONATES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;19(69):79-87. Available from: https://sid.ir/paper/46131/en

IEEE: Copy

R. SHIARI, M.M. NASEHI, SH. FARIVAR, and BIZHAN HATAMIAN, “THE SURVEY OF ANTI-INFLAMMATORY EFFECT OF BISPHOSPHONATES,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 19, no. 69, pp. 79–87, 2009, [Online]. Available: https://sid.ir/paper/46131/en

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