APPEARANCE OF THE INTESTINAL GOBLET CELLS IN FETUS WITH FUCOSE- SPECIFIC GLYCOPROTEIN SECRETION

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ARVAND M.; GANGIE F.K.; FAZEL A.R.

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Journal: Medical Journal of Tabriz University of Medical Sciences Year:2001 | Volume:35 | Issue:49 Page(s): 3-10

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Title

APPEARANCE OF THE INTESTINAL GOBLET CELLS IN FETUS WITH FUCOSE- SPECIFIC GLYCOPROTEIN SECRETION

Author(s)

ARVAND M. | GANGIE F.K. | FAZEL A.R. | Issue Writer Certificate

Keywords

INTESTINAL GOBLET CELLSQ4

LECTIN HISTOCHEMISTRYQ4

INTESTINAL DEVELOPMENTQ4

Abstract

Background and Objectives: Lectin histochemical studies have been reported to characterize terminal sugars of rat embryonic goblet cells which reside throughout the length of the small and large intestine.Methodology: Lectin from dolichos biflorus (DBA) which react specifically with N-acetyl - galactosamine, an adult terminal sugar for INTESTINAL GOBLET CELLS was used for this study .In addition to this, three fucose binding lectins from aleuria aurantia (OFA), lotus tetragonobolus (LTA) and ulex europeus (UEA-1) which have different binding characteristics to terminal fucose, were also utilized.Results: The INTESTINAL GOBLET CELLS started to appear on day 17 of gestation in rat embryos. These cells reacted strongly with OFA in both small and large section of intestine. UEA-1 reacted only with the goblet cells of the large intestine. LTA reaction was very poor while, DBA did not react with any goblet cells during INTESTINAL DEVELOPMENT.Conclusion: The results observed indicate that embryonic glycoconjugates of goblet cell mucine are different from their adult form, and also fucose plays an important role for intestinal goblet cell development. It also might have protective and maintenance activities for mucus blanket, during late fetal period.

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APA: Copy

ARVAND, M., GANGIE, F.K., & FAZEL, A.R.. (2001). APPEARANCE OF THE INTESTINAL GOBLET CELLS IN FETUS WITH FUCOSE- SPECIFIC GLYCOPROTEIN SECRETION . MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 35(49), 3-10. SID. https://sid.ir/paper/47066/en

Vancouver: Copy

ARVAND M., GANGIE F.K., FAZEL A.R.. APPEARANCE OF THE INTESTINAL GOBLET CELLS IN FETUS WITH FUCOSE- SPECIFIC GLYCOPROTEIN SECRETION . MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2001;35(49):3-10. Available from: https://sid.ir/paper/47066/en

IEEE: Copy

M. ARVAND, F.K. GANGIE, and A.R. FAZEL, “APPEARANCE OF THE INTESTINAL GOBLET CELLS IN FETUS WITH FUCOSE- SPECIFIC GLYCOPROTEIN SECRETION ,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 35, no. 49, pp. 3–10, 2001, [Online]. Available: https://sid.ir/paper/47066/en

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