ANTI-NOCICEPTIVE EFFECT OF ARCTIUM LAPPA L. LEAFH HYDROETHANOLIC EXTRACT IN MALE MICE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Jaani Somaye; MIRAZI NASER

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2018 | Volume:39 | Issue:5 Page(s): 28-35

Download Full-Text

Persian Verion

View:

908

Download:

Cites:

Information Journal Paper

Title

ANTI-NOCICEPTIVE EFFECT OF ARCTIUM LAPPA L. LEAFH HYDROETHANOLIC EXTRACT IN MALE MICE

Author(s)

Jaani Somaye | MIRAZI NASER | Issue Writer Certificate

Keywords

ARCTIUMLAPPAQ1

ANTINOCICEPTIVEQ3

MICEQ2

Abstract

Background: Pain is a sign to identify the disease and mostly has a protective effect. Several side effects of chemical drugs caused more likely people are to use herbal treatment. Use of drugs and medicinal plants are common methods of pain control. The aim of this study was to evaluate the ANTINOCICEPTIVE effects of ARCTIUMLAPPA L. leafh’ shydroethanolic extract (AHE) in male MICE. Methods: This study contained 72 male MICE with the weight of 25± 30 gr. MICEs were divided randomly in two groups with 6 subgroups (n=6 for each group) including: Control group treated with AHE at doses of 100, 200 and 400mg/kg, morphine (1mg/kg) and case group treated with naloxone (2mg/kg) with dose 200 mg/kg of extract. In order to evaluate the analgesic effect of the extract, writhing and tail flick tests were used. Results: Doses of 200 and 400mg/kg of AHE significantly increased pain threshold compared with the control group in writhing and tail flick tests (P<0. 01). Also dose 400mg/kg of AHE have been showed mostly analgesic effect especially in writhing test compared with morphine group (P<0. 001). Conclusion: Analgesic effect of the AHE was observed in the tail flick and writhing tests and this analgesic effect of extract probably related to activation of opioid system.

Cites

No record.

References

No record.

Cite

APA: Copy

Jaani, Somaye, & MIRAZI, NASER. (2018). ANTI-NOCICEPTIVE EFFECT OF ARCTIUM LAPPA L. LEAFH HYDROETHANOLIC EXTRACT IN MALE MICE. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 39(5 ), 28-35. SID. https://sid.ir/paper/47121/en

Vancouver: Copy

Jaani Somaye, MIRAZI NASER. ANTI-NOCICEPTIVE EFFECT OF ARCTIUM LAPPA L. LEAFH HYDROETHANOLIC EXTRACT IN MALE MICE. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;39(5 ):28-35. Available from: https://sid.ir/paper/47121/en

IEEE: Copy

Somaye Jaani, and NASER MIRAZI, “ANTI-NOCICEPTIVE EFFECT OF ARCTIUM LAPPA L. LEAFH HYDROETHANOLIC EXTRACT IN MALE MICE,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 39, no. 5 , pp. 28–35, 2018, [Online]. Available: https://sid.ir/paper/47121/en

Related Journal Papers