EFFECTS OF MEPARTRICIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA

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SAMADZADEH S.; SAMSAMI F.; ABDOLHOSEINZADEH N.; GHAVAM F.

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2001 | Volume:- | Issue:50 Page(s): 57-61

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Title

EFFECTS OF MEPARTRICIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA

Author(s)

SAMADZADEH S. | SAMSAMI F. | ABDOLHOSEINZADEH N. | GHAVAM F. | Issue Writer Certificate

Keywords

MEPARTRICINQ4

PROSTATEQ3

HYPERPLASIAQ4

Abstract

Background and Objectives: MEPARTRICIN is a semi-synthetic anti-fungal and anti-parasitic drug which is produced by culture of Streptomyces aureofaciens. The use of MEPARTRICIN on patients with benign prostatic HYPERPLASIA (BPH) has been experienced with good therapeutic results and less side effects. The aim of this study was to evaluate the effects of this drug on the patients with benign prostatic HYPERPLASIA and to observe for any side effects.Materials and Methods: 45 patients with BPH were selected and MEPARTRICIN was administered three times daily for 30 days. At the end of treatment and after 3, 6, 12 and 18 months, effects of the drug on these patients were evaluated.Results: There was a marked decrease in the volume of urine residue and increase in urine flow during and 3 months after treatment, but no change was noticed in the later months. No effect was observed on routine biochemical laboratory tests except for cholesterol and triglyceride which were declined in 8 patients. Side effects were seen in 7 patients which consisted of dyspepsia in 3, nausea in 1, constipation in 1 and decrease in libido in 2 cases.Conclusion: The use of MEPARTRICIN caused a marked decrease in urine volume and an increase in urine flow without any negative effect on hematological and biochemical tests.

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APA: Copy

SAMADZADEH, S., SAMSAMI, F., ABDOLHOSEINZADEH, N., & GHAVAM, F.. (2001). EFFECTS OF MEPARTRICIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA . MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, -(50), 57-61. SID. https://sid.ir/paper/47522/en

Vancouver: Copy

SAMADZADEH S., SAMSAMI F., ABDOLHOSEINZADEH N., GHAVAM F.. EFFECTS OF MEPARTRICIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA . MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2001;-(50):57-61. Available from: https://sid.ir/paper/47522/en

IEEE: Copy

S. SAMADZADEH, F. SAMSAMI, N. ABDOLHOSEINZADEH, and F. GHAVAM, “EFFECTS OF MEPARTRICIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA ,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. -, no. 50, pp. 57–61, 2001, [Online]. Available: https://sid.ir/paper/47522/en

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