COMPARISON OF TWO TESTS (RAPID UREASE AND ELISA) FOR DIAGNOSIS OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH UPPER GASTROINTESTINAL DISCOMFORT

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RAHNAMA B.; FATAHI E.

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2002 | Volume:- | Issue:53 Page(s): 19-23

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Title

COMPARISON OF TWO TESTS (RAPID UREASE AND ELISA) FOR DIAGNOSIS OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH UPPER GASTROINTESTINAL DISCOMFORT

Author(s)

RAHNAMA B. | FATAHI E. | Issue Writer Certificate

Keywords

HELICOBACTER PYLORIQ3

PEPTIC ULCERQ3

RAPID UREASE TESTQ4

ELISAQ4

Abstract

Background and Objectives: HELICOBACTER PYLORI (HP) infection in man has several disease outcomes, varying from asymptomatic chronic gastric inflammation to HP-associated dyspepsia, PEPTIC ULCER disease, gastric adenocarcinoma, and MALT lymphoma. This study was undertaken to evaluate HELICOBACTER PYLORI infection and assess the sensitivity, specificity, positive and negative predictive value of two commonly used diagnostic tests for HELICOBACTER PYLORI i.e. Rapid urease and ELISA tests.Materials and Methods: The present prospective study was performed on 120 patients (with dyspepsia) referred to Imam Khomeini hospital in Tabriz. Antral biopsy specimens were taken for RAPID UREASE TEST and IgG anti-HELICOBACTER PYLORI was evaluated with a serological test (ELISA). If both the tests were positive, the patients were taken into account to be HELICOBACTER PYLORI positive. Results: In this study, patients with two positive tests (rapid urease as well as ELISA) were considered to be HELICOBACTER PYLORI positive. Of the total patients studied, 86 (71.6%) were found HELICOBACTER PYLORI positive and 34 (28.4%) were negative. The sensitivity, specificity, positive and negative predictive values were as follows respectively: RAPID UREASE TEST 89%, 92.6%, 97%, 75.8% and for ELISA test: 97%, 75.8%, 89%, 92.6%. Conclusions: Our results indicate that due to non- invasiveness and high sensitivity of ELISA method in comparison to RAPID UREASE TEST, it is favourable to perform this test for H.pylori in suspicious patients and if the test is positive with clinical presentation, endoscopic procedures should be applied.

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APA: Copy

RAHNAMA, B., & FATAHI, E.. (2002). COMPARISON OF TWO TESTS (RAPID UREASE AND ELISA) FOR DIAGNOSIS OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH UPPER GASTROINTESTINAL DISCOMFORT . MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, -(53), 19-23. SID. https://sid.ir/paper/47612/en

Vancouver: Copy

RAHNAMA B., FATAHI E.. COMPARISON OF TWO TESTS (RAPID UREASE AND ELISA) FOR DIAGNOSIS OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH UPPER GASTROINTESTINAL DISCOMFORT . MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2002;-(53):19-23. Available from: https://sid.ir/paper/47612/en

IEEE: Copy

B. RAHNAMA, and E. FATAHI, “COMPARISON OF TWO TESTS (RAPID UREASE AND ELISA) FOR DIAGNOSIS OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH UPPER GASTROINTESTINAL DISCOMFORT ,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. -, no. 53, pp. 19–23, 2002, [Online]. Available: https://sid.ir/paper/47612/en

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