THE STUDY OF PHENOL INTERVENTIONAL EFFECTS ON MOUSE ORGANOGENESIS

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JALALI M.; NIKRAVESH M.R.

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Paper Information

Journal: PHARMACEUTICAL SCIENCES Year:2001 | Volume:- | Issue:1 Page(s): 15-22

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Information Journal Paper

Title

THE STUDY OF PHENOL INTERVENTIONAL EFFECTS ON MOUSE ORGANOGENESIS

Author(s)

JALALI M. | NIKRAVESH M.R. | Issue Writer Certificate

Keywords

PHENOLQ3

ABNORMALITYQ3

PREGNANCYQ3

MOUSEQ2

Abstract

PHENOL with its application in the preparation of many chemical compounds, drugs and sanitate agents is used. Therefore during PREGNANCY contact with PHENOL it can absorbe and produce, maternal toxicity and affect on embryonic evolution. The aim of this investigation was to study the teratogenic effects of PHENOL in the developing MOUSE. For this study 14 virgin mice balb/c were mated. The pregnant mice were divided to experimental and control group. Between 7 to 11 postmating days, 50 mg/kg PHENOL (merk) interaperitonealy injected daily in experimental and the same manner control group received physiological serum. At the last day of PREGNANCY, all of cases (experimental and control) were anestetised, sacrificed and their fetuses collected, coded and all of malformations examined. The results show a decrease of population and high incidence of various abnormalities (such as exencephaly, limbs and skeletal defects) in experimental fetuses in comparison with control group.

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APA: Copy

JALALI, M., & NIKRAVESH, M.R.. (2001). THE STUDY OF PHENOL INTERVENTIONAL EFFECTS ON MOUSE ORGANOGENESIS. PHARMACEUTICAL SCIENCES, -(1), 15-22. SID. https://sid.ir/paper/48475/en

Vancouver: Copy

JALALI M., NIKRAVESH M.R.. THE STUDY OF PHENOL INTERVENTIONAL EFFECTS ON MOUSE ORGANOGENESIS. PHARMACEUTICAL SCIENCES[Internet]. 2001;-(1):15-22. Available from: https://sid.ir/paper/48475/en

IEEE: Copy

M. JALALI, and M.R. NIKRAVESH, “THE STUDY OF PHENOL INTERVENTIONAL EFFECTS ON MOUSE ORGANOGENESIS,” PHARMACEUTICAL SCIENCES, vol. -, no. 1, pp. 15–22, 2001, [Online]. Available: https://sid.ir/paper/48475/en

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