QUALITY ASSESSMENT OF GLUCOSAMINE PREPARATIONS AVAILABLE IN DRUG MARKET OF IRAN

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NEMATI M.; VALIZADEH H.; ANSARIN M.; GHADERI FARANAK

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Journal: PHARMACEUTICAL SCIENCES Year:2006 | Volume:- | Issue:3 Page(s): 7-12

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Information Journal Paper

Title

QUALITY ASSESSMENT OF GLUCOSAMINE PREPARATIONS AVAILABLE IN DRUG MARKET OF IRAN

Author(s)

NEMATI M. | VALIZADEH H. | ANSARIN M. | GHADERI FARANAK | Issue Writer Certificate

Keywords

GLUCOSAMINEQ2

PHARMACEUTICSQ2

QUALITY CONTROLQ2

Abstract

Objectives: the purpose of this study was the evaluation of pharmaceutical properties and QUALITY CONTROL of GLUCOSAMINE preparations available in Iran drug market. Methods: 10 commercial products were selected and evaluated for some Pharmaceutical characteristics such as content uniformity, assay, weight variation and dissolution test. Dِetermination of GLUCOSAMINE was performed according to a new high performance liquid chromatography (HPLC) method developed for the first time. The method was based on pre column derivatization of GLUCOSAMINE by orthophthaldialdehyde (OPA). Results: the results of these tests about 10 commercial products were as follow: assay was between 13.69% and 138.72%, for content uniformity RSD% was between 4.17 and 26.60, weight variation had RSD% between 0.69 and 7.5. Dissolved GLUCOSAMINE (%) in dissolution test was between 20.03% and 98.71%. Similarity factor test on the results of dissolution test showed that at least 3 commercial products have not been in an acceptable range in comparison with reference product (No.2). Conclusion: according to these results, good controls on the quality of food supplements are required.

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APA: Copy

NEMATI, M., VALIZADEH, H., ANSARIN, M., & GHADERI, FARANAK. (2006). QUALITY ASSESSMENT OF GLUCOSAMINE PREPARATIONS AVAILABLE IN DRUG MARKET OF IRAN. PHARMACEUTICAL SCIENCES, -(3), 7-12. SID. https://sid.ir/paper/48525/en

Vancouver: Copy

NEMATI M., VALIZADEH H., ANSARIN M., GHADERI FARANAK. QUALITY ASSESSMENT OF GLUCOSAMINE PREPARATIONS AVAILABLE IN DRUG MARKET OF IRAN. PHARMACEUTICAL SCIENCES[Internet]. 2006;-(3):7-12. Available from: https://sid.ir/paper/48525/en

IEEE: Copy

M. NEMATI, H. VALIZADEH, M. ANSARIN, and FARANAK GHADERI, “QUALITY ASSESSMENT OF GLUCOSAMINE PREPARATIONS AVAILABLE IN DRUG MARKET OF IRAN,” PHARMACEUTICAL SCIENCES, vol. -, no. 3, pp. 7–12, 2006, [Online]. Available: https://sid.ir/paper/48525/en

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