STUDIES ON THE EFFECT OF SOLVENT ON THE EFFICIENCY OF SUNSCREEN PRODUCTS

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SIAHI SHADBAD M.R.; JAVADZADEH Y.; MAHDAVIZADEH F.; NOKHOUDCHI A.

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Journal: PHARMACEUTICAL SCIENCES Year:2005 | Volume:- | Issue:3 Page(s): 1-7

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Information Journal Paper

Title

STUDIES ON THE EFFECT OF SOLVENT ON THE EFFICIENCY OF SUNSCREEN PRODUCTS

Author(s)

SIAHI SHADBAD M.R. | JAVADZADEH Y. | MAHDAVIZADEH F. | NOKHOUDCHI A. | Issue Writer Certificate

Keywords

ANTI SOLARQ2

SOLVENTQ2

BEZOPHENONQ2

PARSOLQ2

Abstract

Objectives: SOLVENTs are one of the most important ingredients in the preparation of hygienic and cosmetic products. Nowadays the adverse effects of the sun light on the skin such as stinging, erythema and finally skin cancer have been known. Therefore the use of anti preparations is common. In this study we tried to evaluate the effect of the SOLVENTs in altering of absorption amount and λmax of UVB for the chemical substance of products. METHODS: For this mean ANTI SOLAR materials were solved in SOLVENTs i.e. water, sorbitol, ethanol, propylene glycol and glycerin. Then spectra and absorption intensities of them were measured in 5 nm intervals using by spectrophotometer instrument. Finally according to them maximum absorption. Shift amount, area under the curve and relative efficacy of the ANTI SOLAR substance were calculated. RESULTS: The results showed that the type of SOLVENT had significantly effect on lmax. It should be considered that in the formulations containing PARSOL 5000, using water and sorbitol as a SOLVENT is not reasonable. Because these SOLVENTs will shift the lmax sunscreen and the efficacy of the preparation will be lost Most of the SOLVENTs altered the lmax the benzophenon toward lower wave lengths. It was showed that PABA and PARSOL HS had low sensitivity to the type of SOLVENT among other sunscreens. Then it is possible to use most of the SOLVENTs in formulations as sunscreen products. It is necessary to say that the SPF of the product may be changed because of altering the lmax and absorption intensity of the ANTI SOLAR substance by the SOLVENTs. CONCLUSION: Then it is possible to choose proper SOLVENT for the each of above ANTI SOLAR materials.

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APA: Copy

SIAHI SHADBAD, M.R., JAVADZADEH, Y., MAHDAVIZADEH, F., & NOKHOUDCHI, A.. (2005). STUDIES ON THE EFFECT OF SOLVENT ON THE EFFICIENCY OF SUNSCREEN PRODUCTS. PHARMACEUTICAL SCIENCES, -(3), 1-7. SID. https://sid.ir/paper/48550/en

Vancouver: Copy

SIAHI SHADBAD M.R., JAVADZADEH Y., MAHDAVIZADEH F., NOKHOUDCHI A.. STUDIES ON THE EFFECT OF SOLVENT ON THE EFFICIENCY OF SUNSCREEN PRODUCTS. PHARMACEUTICAL SCIENCES[Internet]. 2005;-(3):1-7. Available from: https://sid.ir/paper/48550/en

IEEE: Copy

M.R. SIAHI SHADBAD, Y. JAVADZADEH, F. MAHDAVIZADEH, and A. NOKHOUDCHI, “STUDIES ON THE EFFECT OF SOLVENT ON THE EFFICIENCY OF SUNSCREEN PRODUCTS,” PHARMACEUTICAL SCIENCES, vol. -, no. 3, pp. 1–7, 2005, [Online]. Available: https://sid.ir/paper/48550/en

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