SERUM LEVELS OF SE, ZN, CU AND CU / ZN RATIO IN IRANIAN BREAST CANCER PATIENTS

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ZARGHAMI N.A.; ASADI J.; MAHBOUB S.A.; MOHAMMADZADEH GH.; MOHAJERI ABAS

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Information Journal Paper

Title

SERUM LEVELS OF SE, ZN, CU AND CU / ZN RATIO IN IRANIAN BREAST CANCER PATIENTS

Author(s)

Keywords

BREAST CANCERQ2

ZNQ2

CUQ2

SEQ2

Abstract

Objectives: BREAST CANCER is the most common cancer in women. Combinations of internal and external factors like as trace elements are involved in initial development of breast tumors. The aim of this study was to evaluate and compare SErum levels of ZN, CU, SE and CU/Zn ratio in BREAST CANCER patients and control group. Methods: This study was a descriptive cross SEctional and composed of 50 women diagnosed with BREAST CANCER and 50 normal individuals. The age range of patients and controls was between 30-50 yrs. Blood samples were obtained and SErum isolated immediately. Levels of ZN, CU and SE were measured in blood SErum using atomic absorption spectrophotometry (AAS) and Graphite furnace atomic absorption spectrophotometry. Results: Mean SErum levels of ZN, CU and SE were 0.969±.19, 1.47±.48 mg/Land 60.04±23.38mg/L, respectively, in BREAST CANCER patients. The mean concentrations of ZN, CU and SE SErum in normal individual were 1.07±.35, 1.09±.20 mg/L and 92.42±18.70mg/L respectively. There was also a significant difference between CU levels of patient and control group (p<0.001). In addition, the CU/Zn ratio in BREAST CANCER patients and controls were 1.52 and 1.12, respectively. This difference was statistically significant (p<0.001). There was a significant difference between SE levels of patients and control group (p<0.001). Conclusion: Based on obtained results, changes of SErum level of trace elements SE, ZN and CU could have likely biological role in the initiation or progression of BREAST CANCER.

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APA: Copy

ZARGHAMI, N.A., ASADI, J., MAHBOUB, S.A., MOHAMMADZADEH, GH., & MOHAJERI, ABAS. (2008). SERUM LEVELS OF SE, ZN, CU AND CU / ZN RATIO IN IRANIAN BREAST CANCER PATIENTS. PHARMACEUTICAL SCIENCES, -(1), 27-32. SID. https://sid.ir/paper/48595/en

Vancouver: Copy

ZARGHAMI N.A., ASADI J., MAHBOUB S.A., MOHAMMADZADEH GH., MOHAJERI ABAS. SERUM LEVELS OF SE, ZN, CU AND CU / ZN RATIO IN IRANIAN BREAST CANCER PATIENTS. PHARMACEUTICAL SCIENCES[Internet]. 2008;-(1):27-32. Available from: https://sid.ir/paper/48595/en

IEEE: Copy

N.A. ZARGHAMI, J. ASADI, S.A. MAHBOUB, GH. MOHAMMADZADEH, and ABAS MOHAJERI, “SERUM LEVELS OF SE, ZN, CU AND CU / ZN RATIO IN IRANIAN BREAST CANCER PATIENTS,” PHARMACEUTICAL SCIENCES, vol. -, no. 1, pp. 27–32, 2008, [Online]. Available: https://sid.ir/paper/48595/en

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