EFFECTS OF CLONIDINE IN PERIOPERATIVE HEMODYNAMIC AND ANESTHETIC REQUIREMENTS IN OLD PATIENTS

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PAYROWIFAR A.; AIDI M.M; KOLAHDOUZAN KH.

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Journal: PHARMACEUTICAL SCIENCES Year:2003 | Volume:- | Issue:2 Page(s): 9-16

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Title

EFFECTS OF CLONIDINE IN PERIOPERATIVE HEMODYNAMIC AND ANESTHETIC REQUIREMENTS IN OLD PATIENTS

Author(s)

PAYROWIFAR A. | AIDI M.M | KOLAHDOUZAN KH. | Issue Writer Certificate

Keywords

CLONIDINEQ2

OLD PATIENTSQ3

GENERAL ANESTHESIAQ3

HEMODYNAMICQ3

Abstract

The aim of this was assessment effects of oral CLONIDINE on perioprative HEMODYNAMIC and anesthetic requirement in OLD PATIENTS. In a prospective study, 40 patient randomly divided in two group. A (Study group) and group B (Control group), each of them had 20 patients. All of the patients were in ASA class II with mean age of (72.6l±7.8y), and sex distribution of 29 males and 11 Females. The patients of group A received low dose oral CLONIDINE (2.5µg/kg) and diazepam (0.1 mg/kg) and those of control group recived diazepam (0.1 mg/kg), 90 minute before induction of GA. Drugs used for induction of both groups included fentanyl l.5µg, thiopantal5mglkg, succinylcholine 1mg/kg, lidocaine 1-1.5mglkg and maintenance of anesthesia included O2 (50 Vol%), N2O(50 Vol%) and 0.50/0-1.5% of halothune. Blood pressure (sys, dia and MAP) and HR were recorded after administration of drugs and during anesthesia. There was no significant difference between both groups regarding in age, weight and sex (P>0.05). Average MAP and sys. BP after laryngoscopy and intubation compared with before them reduced slowly after 5th min. Systolic BP and MAP were more stable in group A. likely HR increased after laryngoscopy and intubation which was more stable in group A. Anesthetic requirement during maintenance of anesthesia reduced in both groups although was greater in group B. Oral CLONIDINE with diazepam, as a premeditation, compared with oral diazepam have more greater and apparent effects in prevention of stress of laryngoscopy and intubation, stability of homodynamic and reduction in halothune requirement, especially in aged patients in ASA class n.

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APA: Copy

PAYROWIFAR, A., AIDI, M.M, & KOLAHDOUZAN, KH.. (2003). EFFECTS OF CLONIDINE IN PERIOPERATIVE HEMODYNAMIC AND ANESTHETIC REQUIREMENTS IN OLD PATIENTS. PHARMACEUTICAL SCIENCES, -(2), 9-16. SID. https://sid.ir/paper/48654/en

Vancouver: Copy

PAYROWIFAR A., AIDI M.M, KOLAHDOUZAN KH.. EFFECTS OF CLONIDINE IN PERIOPERATIVE HEMODYNAMIC AND ANESTHETIC REQUIREMENTS IN OLD PATIENTS. PHARMACEUTICAL SCIENCES[Internet]. 2003;-(2):9-16. Available from: https://sid.ir/paper/48654/en

IEEE: Copy

A. PAYROWIFAR, M.M AIDI, and KH. KOLAHDOUZAN, “EFFECTS OF CLONIDINE IN PERIOPERATIVE HEMODYNAMIC AND ANESTHETIC REQUIREMENTS IN OLD PATIENTS,” PHARMACEUTICAL SCIENCES, vol. -, no. 2, pp. 9–16, 2003, [Online]. Available: https://sid.ir/paper/48654/en

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