EXTRA CELLULAR SUPEROXIDE DISMUTASE ACTIVITY IN LUNG INJURIES DUE TO SULFUR MUSTARD

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SHOHRATI M.; GHANEEI MOSTAFA; SHAMSPOUR N.; JAFARI MAHVASH; NOUROUZI ABDI KHASMAKHI M.

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Journal: Journal of Inflammatory Diseases Year:2009 | Volume:12 | Issue:4 (49) Page(s): 5-11

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Title

EXTRA CELLULAR SUPEROXIDE DISMUTASE ACTIVITY IN LUNG INJURIES DUE TO SULFUR MUSTARD

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Keywords

OXIDE DISMUTASEQ3

SULFUR MUSTARDQ3

CELLSQ3

LUNGQ2

WOUNDS AND INJURIESQ3

MUSTARDQ4

CHEMICAL WARFARE AGENTSQ3

Abstract

Background: Pulmonary complications are known to occur in over half of the patients exposed to MUSTARD/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> SULFUR MUSTARD (SM). There is controversial regarding the role of extracellular superOXIDE DISMUTASE (EC-SOD) in different airway diseases.Objective: The aim of this study was to evaluate the correlation between LUNG function and ECSOD activity in patient with LUNG injuries due to SM.Methods: This was a case-control study carried out on 220 patients with LUNG complication due to SM in the city of Sardasht (Iran) in 2007. Spirometry was used to assess pulmonary function followed by measurement of EC-SOD activity. T test was employed to examine the differences between study groups. Pearson correlation coefficient was also used to find the possible correlation between EC-SOD activity and the LUNG function.Findings: The mean EC-SOD activity in control group (70.5±10.8U/L) was higher than that of moderate to severe group 67.0±6.1 U/L (p<0.001). There was no significant difference for mean EC-SOD activity between mild and control groups. Significant and direct association between ECSOD activities and LUNG function was established (p<0.001).Conclusion: According to our findings, inactivation of EC-SOD may lead to progressive inflammation and LUNG injury due to MUSTARD/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> SULFUR MUSTARD.

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APA: Copy

SHOHRATI, M., GHANEEI, MOSTAFA, SHAMSPOUR, N., JAFARI, MAHVASH, & NOUROUZI ABDI KHASMAKHI, M.. (2009). EXTRA CELLULAR SUPEROXIDE DISMUTASE ACTIVITY IN LUNG INJURIES DUE TO SULFUR MUSTARD. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 12(4 (49)), 5-11. SID. https://sid.ir/paper/48941/en

Vancouver: Copy

SHOHRATI M., GHANEEI MOSTAFA, SHAMSPOUR N., JAFARI MAHVASH, NOUROUZI ABDI KHASMAKHI M.. EXTRA CELLULAR SUPEROXIDE DISMUTASE ACTIVITY IN LUNG INJURIES DUE TO SULFUR MUSTARD. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2009;12(4 (49)):5-11. Available from: https://sid.ir/paper/48941/en

IEEE: Copy

M. SHOHRATI, MOSTAFA GHANEEI, N. SHAMSPOUR, MAHVASH JAFARI, and M. NOUROUZI ABDI KHASMAKHI, “EXTRA CELLULAR SUPEROXIDE DISMUTASE ACTIVITY IN LUNG INJURIES DUE TO SULFUR MUSTARD,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 12, no. 4 (49), pp. 5–11, 2009, [Online]. Available: https://sid.ir/paper/48941/en

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