DETERMINING MINIMUM INHIBITORY CONCENTRATION GROWTH RATE AND SENSITIVITY OF YERSINIA TO BETA-LACTAM ANTIBIOTICS

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SOLTAN DALLAL M.M.; SHARIFI YAZDI M.K.; VAHEDI S.

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Journal: Journal of Inflammatory Diseases Year:2016 | Volume:20 | Issue:5 (88) Page(s): 11-18

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Title

DETERMINING MINIMUM INHIBITORY CONCENTRATION GROWTH RATE AND SENSITIVITY OF YERSINIA TO BETA-LACTAM ANTIBIOTICS

Author(s)

SOLTAN DALLAL M.M. | SHARIFI YAZDI M.K. | VAHEDI S. | Issue Writer Certificate

Keywords

YERSINIA SPPQ3

BETA LACTAMQ2

MINIMUM INHIBITORY CONCENTRATION (MIC)Q2

AMPICILLINQ4

CEFAZOLINQ3

CEFOTAXIMEQ3

Abstract

Background: Diarrhea is one of the most important causes of children mortality in developing countries. Gastroenteritis causes mortality in children younger than five years old annually. The presence of antibiotics resistance species among these bacteria are major health problems.Objective: This study aimed to determine the antibiotic susceptibility and MIC50%, MIC90% of Yersinia to three beta-lactam antibiotics.Methods: This experimental study was determined sensitivity of different species of Yersinia to three beta-lactam antibiotics (Ampicillin-Cefazolin-Cefotaxime). In total 50 species (39 from different human sources, environments, foods and 11 from Pasteur institutions in Paris) were used. Minimum inhibitory concentration (MIC) was carried out by serial dilution method.Findings: Among three tested antibiotics, the lowest MIC 50%, MIC 90% were obtained for CEFOTAXIME (£0.125mg/ml and 0.5mg/ml). All the tested species showed resistance to AMPICILLIN and very low sensitivity toward CEFAZOLIN.Conclusion: The results showed that CEFOTAXIME was more effective against Yersinia species in compared to AMPICILLIN and CEFAZOLIN.

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APA: Copy

SOLTAN DALLAL, M.M., SHARIFI YAZDI, M.K., & VAHEDI, S.. (2016). DETERMINING MINIMUM INHIBITORY CONCENTRATION GROWTH RATE AND SENSITIVITY OF YERSINIA TO BETA-LACTAM ANTIBIOTICS. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 20(5 (88)), 11-18. SID. https://sid.ir/paper/49097/en

Vancouver: Copy

SOLTAN DALLAL M.M., SHARIFI YAZDI M.K., VAHEDI S.. DETERMINING MINIMUM INHIBITORY CONCENTRATION GROWTH RATE AND SENSITIVITY OF YERSINIA TO BETA-LACTAM ANTIBIOTICS. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2016;20(5 (88)):11-18. Available from: https://sid.ir/paper/49097/en

IEEE: Copy

M.M. SOLTAN DALLAL, M.K. SHARIFI YAZDI, and S. VAHEDI, “DETERMINING MINIMUM INHIBITORY CONCENTRATION GROWTH RATE AND SENSITIVITY OF YERSINIA TO BETA-LACTAM ANTIBIOTICS,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 20, no. 5 (88), pp. 11–18, 2016, [Online]. Available: https://sid.ir/paper/49097/en

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