ANXIOLYTIC EFFECTS OF VALEPOTRIATES EXTRACTED FROM VALERIANA OFFICINALIS L. IN RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SANAGOUY MOTLAGH H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Inflammatory Diseases Year:2008 | Volume:12 | Issue:3 (48) Page(s): 63-67

Download Full-Text

Persian Verion

View:

1,585

Download:

Cites:

Information Journal Paper

Title

ANXIOLYTIC EFFECTS OF VALEPOTRIATES EXTRACTED FROM VALERIANA OFFICINALIS L. IN RATS

Author(s)

SANAGOUY MOTLAGH H. | Issue Writer Certificate

Keywords

ANXIETYQ2

VALEPOTRIATESQ3

VALERIANQ3

RATQ2

Abstract

Background: ANXIETY is a common disorder attacking many people in the society and often accompanied by physiological sensations such as tachycardia, chest pain, shortness of breath, insensitivity, and so on.Objective: The purpose of present study was to characterize the putative anxiolytic-like effects of VALEPOTRIATES (dichloromethane extracts of VALERIAN) using the elevated plus maze (EPM) in RATs.Materials and Methods: This was an experimental study carried out at Biology Department of Azad Islamic University in Karaj (Iran) in 2006. VALEPOTRIATES was dissolved in DMSO and orally administered at different doses to adult male Wistar RATs, 0.5, 1.5 and 3 hours before behavioral evaluation in an EPM. Control RATs were treated with an equal volume of DMSO. Data were evaluated using SPSS and variance analysis.Findings: Single treatment with VALEPOTRIATES at two concentrations of 0.1, and 0.2 g/kg caused a statically significant increased time-spent and arm entries into open arms of EPM compared to control group (p<0.05). However, animal’s locomotor activity found to be unchanged.Conclusion: Based on our data, it seems that VALEPOTRIATES to have a potential as an effective anxiolytic agent.

Cites

No record.

References

No record.

Cite

APA: Copy

SANAGOUY MOTLAGH, H.. (2008). ANXIOLYTIC EFFECTS OF VALEPOTRIATES EXTRACTED FROM VALERIANA OFFICINALIS L. IN RATS. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 12(3 (48)), 63-67. SID. https://sid.ir/paper/49252/en

Vancouver: Copy

SANAGOUY MOTLAGH H.. ANXIOLYTIC EFFECTS OF VALEPOTRIATES EXTRACTED FROM VALERIANA OFFICINALIS L. IN RATS. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2008;12(3 (48)):63-67. Available from: https://sid.ir/paper/49252/en

IEEE: Copy

H. SANAGOUY MOTLAGH, “ANXIOLYTIC EFFECTS OF VALEPOTRIATES EXTRACTED FROM VALERIANA OFFICINALIS L. IN RATS,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 12, no. 3 (48), pp. 63–67, 2008, [Online]. Available: https://sid.ir/paper/49252/en

Related Journal Papers