The Effects of Regular Aerobic Exercise on the Serum levels of Plasminogen Activator Inhibitor-1 and Adiponectin in Obese Girls

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HABIBIAN MASOUMEH; Rezaye Mousavi Seyed Abdolvahab

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Journal: Journal of Inflammatory Diseases (The Journal of Qazvin University of Medical Science) Year:2019 | Volume:23 | Issue:5 (106) Page(s): 418-428

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Information Journal Paper

Title

The Effects of Regular Aerobic Exercise on the Serum levels of Plasminogen Activator Inhibitor-1 and Adiponectin in Obese Girls

Author(s)

HABIBIAN MASOUMEH | Rezaye Mousavi Seyed Abdolvahab | Issue Writer Certificate

Keywords

AdiponectinQ2

Aerobic exerciseQ1

Plasminogen Activator Inhibitor 1Q1

ObesityQ2

Abstract

Background The modulation of the adipokine levels can be important for the long-term prevention of systemic inflammation related to Obesity in children. Objective The current study aimed to investigate the effects of regular Aerobic exercise on the serum levels of plasminogen activator inhibitor-1(PAI-1) and Adiponectin in obese girls. Methods This quasi-experimental study conducted in 2014, 14 obese girls in Galikesh city, Iran who were selected by using purposive and convenience sampling techniques and randomly divided into two groups of control and exercise. Aerobic exercise consisted of exercise movements at 50-70% of maximum heart rate performed at 3 sessions per week for 8 weeks. Fasting blood samples were collected before and 48 hours after the last session of intervention. The PAI-1 and Adiponectin levels were measured by ELISA method. Data were analyzed by independent t-test and one-way analysis of covariance (ANCOVA). The significance level was set at P<0. 05. Findings After 8 weeks of regular Aerobic exercise, serum PAI-1 level and body weight significantly decreased in obese girls, whereas the serum Adiponectin level was significantly increased (P<0. 01). Conclusion findings suggest that regular Aerobic exercise can modulate the adipokine levels in cardiovascular and inflammatory diseases by increasing the Adiponectin level and downregulating the PAI-1 level and hence improve the health of obese girls.

Cites

The Effects of 8 weeks of regular aerobic exercise on the TNF-α levels and lipid profile in obese girls

References

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APA: Copy

HABIBIAN, MASOUMEH, & Rezaye Mousavi, Seyed Abdolvahab. (2019). The Effects of Regular Aerobic Exercise on the Serum levels of Plasminogen Activator Inhibitor-1 and Adiponectin in Obese Girls. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 23(5 (106) ), 418-428. SID. https://sid.ir/paper/49305/en

Vancouver: Copy

HABIBIAN MASOUMEH, Rezaye Mousavi Seyed Abdolvahab. The Effects of Regular Aerobic Exercise on the Serum levels of Plasminogen Activator Inhibitor-1 and Adiponectin in Obese Girls. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2019;23(5 (106) ):418-428. Available from: https://sid.ir/paper/49305/en

IEEE: Copy

MASOUMEH HABIBIAN, and Seyed Abdolvahab Rezaye Mousavi, “The Effects of Regular Aerobic Exercise on the Serum levels of Plasminogen Activator Inhibitor-1 and Adiponectin in Obese Girls,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 23, no. 5 (106) , pp. 418–428, 2019, [Online]. Available: https://sid.ir/paper/49305/en

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