COMPARISON THE EFFECTS OF ETOMIDATE INFUSION VERSUS KETAMINE-MIDAZOLAM-FENTANYL COMBINATION IN SEDATION FOR CATARACT SURGERY

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AGHADAVOUDI OMID; DEHGHAN MARYAM; MONTAZERI KAMRAN

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2013 | Volume:31 | Issue:255 Page(s): 1588-1597

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Title

COMPARISON THE EFFECTS OF ETOMIDATE INFUSION VERSUS KETAMINE-MIDAZOLAM-FENTANYL COMBINATION IN SEDATION FOR CATARACT SURGERY

Author(s)

AGHADAVOUDI OMID | DEHGHAN MARYAM | MONTAZERI KAMRAN | Issue Writer Certificate

Keywords

CATARACT EXTRACTIONQ3

CONSCIOUS SEDATIONQ1

ETOMIDATEQ2

MIDAZOLAMQ3

KETAMINEQ2

Abstract

Background: ETOMIDATE has been used to induce anesthesia with minimum changes in hemodynamic profile in many surgeries. Nevertheless, its infusion for sedation during cataract surgery has been less evaluated.Methods: In a double-blind clinical trial study, 64 patients candidate for cataract surgery under sedation were randomly assigned to receive eitheretomidate-fentanyl (E/F) or KETAMINE-midazolam-fentanyl (K/M/F) combinations. Systolic and diastolic blood pressures, heart rate, oxygen saturation (SaO2), nausea and vomiting, movement frequency, sedation score, recovery duration, and patients’ and surgeon’s satisfaction were recorded during the surgeries.Findings: No statistically significant differences were observed in basic systolic and diastolic blood pressures and heart rate between the groups. But, mean systolic and diastolic blood pressures were significantly higher in K/M/F group during and after the surgery (P<0.050). Systolic and diastolic blood pressures and heart rate did not have significant difference in E/F group (P>0.050) during surgery but there was significant difference in K/M/F group (P<0.050). SaO2 in recovery was significantly higher in E/F group (P<0.001). Incidence of nausea, vomiting and movement episodes, sedation score, and patients’ and surgeon’s satisfaction were the same in both groups. Recovery duration was significantly less in E/F group (P<0.001).Conclusion: Combination of ETOMIDATE and fentanyl for sedation could be as efficient and safe as KETAMINE, MIDAZOLAM, and fentanyl combination in cataract surgery, with less hemodynamic profile changes and recovery time.

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APA: Copy

AGHADAVOUDI, OMID, DEHGHAN, MARYAM, & MONTAZERI, KAMRAN. (2013). COMPARISON THE EFFECTS OF ETOMIDATE INFUSION VERSUS KETAMINE-MIDAZOLAM-FENTANYL COMBINATION IN SEDATION FOR CATARACT SURGERY. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 31(255), 1588-1597. SID. https://sid.ir/paper/49591/en

Vancouver: Copy

AGHADAVOUDI OMID, DEHGHAN MARYAM, MONTAZERI KAMRAN. COMPARISON THE EFFECTS OF ETOMIDATE INFUSION VERSUS KETAMINE-MIDAZOLAM-FENTANYL COMBINATION IN SEDATION FOR CATARACT SURGERY. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2013;31(255):1588-1597. Available from: https://sid.ir/paper/49591/en

IEEE: Copy

OMID AGHADAVOUDI, MARYAM DEHGHAN, and KAMRAN MONTAZERI, “COMPARISON THE EFFECTS OF ETOMIDATE INFUSION VERSUS KETAMINE-MIDAZOLAM-FENTANYL COMBINATION IN SEDATION FOR CATARACT SURGERY,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 31, no. 255, pp. 1588–1597, 2013, [Online]. Available: https://sid.ir/paper/49591/en

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