COMPARISON OF HEMODYNAMIC CHANGES BETWEEN THE COMBINATION OF MIDAZOLAM + FENTANYL AND MIDAZOLAM + MORPHINE FOR SEDATION IN POSTOPERATIVE ICU PATIENTS

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MAHJOUBIFARD M.; ALAVI S.M.

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Paper Information

Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2003 | Volume:23 | Issue:41 Page(s): 53-62

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Title

COMPARISON OF HEMODYNAMIC CHANGES BETWEEN THE COMBINATION OF MIDAZOLAM + FENTANYL AND MIDAZOLAM + MORPHINE FOR SEDATION IN POSTOPERATIVE ICU PATIENTS

Author(s)

MAHJOUBIFARD M. | ALAVI S.M. | Issue Writer Certificate

Keywords

SEDATIONQ4

MIDAZOLAMQ3

FENTANYLQ3

BISPECTRAL INDEXQ3

Abstract

There is no consensus regarding in induction and controlled SEDATION which remain as the most important problems in postoperative ICU patients. The aim of this study was to compare the hemodynamic changes including systolic and diastolic blood pressure, and pulse rate after administration of the combination of MIDAZOLAM + FENTANYL, and MIDAZOLAM + morphine.In a single blind randomized controlled clinical trial, fifty patients who had undergone a major abdominal surgery and needed at least 24 hour mechanical ventilation were enrolled in this study. The age of patients was between 15-40 years. In the group I the patients received MIDAZOLAM and morphine. In group II they received MIDAZOLAM and FENTANYL. SEDATION was measuresd by BIS (BI Spectoral Index).The difference of systolic and diastolic blood pressure in two groups were significant. Systolic blood pressure in group I was (5.4 ± 0.58) and group II (0.24 ± 0.88) [p-value 0.001]. Diastolic blood pressure in group I was (4.12 ± 1.1) and in group II (0.64 ± 1.1) [p-value:0.003]. But there was no significant difference in changes in pulse rate between two groups (p-value=0.4). The combination of MIDAZOLAM and FENTANYL is better in critical postoperative ICU patients whose stability of vital sign is essential.

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APA: Copy

MAHJOUBIFARD, M., & ALAVI, S.M.. (2003). COMPARISON OF HEMODYNAMIC CHANGES BETWEEN THE COMBINATION OF MIDAZOLAM + FENTANYL AND MIDAZOLAM + MORPHINE FOR SEDATION IN POSTOPERATIVE ICU PATIENTS. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 23(41), 53-62. SID. https://sid.ir/paper/63483/en

Vancouver: Copy

MAHJOUBIFARD M., ALAVI S.M.. COMPARISON OF HEMODYNAMIC CHANGES BETWEEN THE COMBINATION OF MIDAZOLAM + FENTANYL AND MIDAZOLAM + MORPHINE FOR SEDATION IN POSTOPERATIVE ICU PATIENTS. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2003;23(41):53-62. Available from: https://sid.ir/paper/63483/en

IEEE: Copy

M. MAHJOUBIFARD, and S.M. ALAVI, “COMPARISON OF HEMODYNAMIC CHANGES BETWEEN THE COMBINATION OF MIDAZOLAM + FENTANYL AND MIDAZOLAM + MORPHINE FOR SEDATION IN POSTOPERATIVE ICU PATIENTS,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 23, no. 41, pp. 53–62, 2003, [Online]. Available: https://sid.ir/paper/63483/en

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