IS STORAGE OF USED STERILE PROPOFOL AT ROOM TEMPERATURE ACCOMPANIED WITH BACTERIAL CONTAMINATION?

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HASHEMI SEYED JALAL; SOLTANINEZHAD H.A.; PARISHANI M.

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Title

IS STORAGE OF USED STERILE PROPOFOL AT ROOM TEMPERATURE ACCOMPANIED WITH BACTERIAL CONTAMINATION?

Author(s)

HASHEMI SEYED JALAL | SOLTANINEZHAD H.A. | PARISHANI M. | Issue Writer Certificate

Keywords

PROPOFOLQ3

BACTERIAL CONTAMINATIONQ3

SYRINGEQ3

VIALQ3

Abstract

Introduction: Lipid-based anesthetic agents such as PROPOFOL support rapid microbial growth at room temperature. Many reports of systemic infections have been-traced to the injection of contaminated PROPOFOL. The results of these studies are different according to the magnitude and the mechanisms of infections. The aim of this study was to evaluate the development of bacterial infection in SYRINGEs and VIALs containing PROPOFOL in relation to duration and the location of storage. Methods: In this experimental study, 2 VIALs of PROPOFOL (50 ml) were selected. Under sterile conditions, 20 ml of each VIAL was aspirated into a sterile SYRINGE and the others were kept in operation room. During one week, the four samples were obtained and aerobic and anaerobic culture was performed. Results: Twenty-four and 48 hours after culture, we evaluated the cultures media for detection of bacteria and colony count. There was no evidence of bacterial growth in any of the samples.Conclusions: With the increasing use of lipid-based medications such as PROPOFOL, which support rapid bacterial growth at room temperature, strict aseptic techniques are essential during the handling to prevent extrinsic contamination. We remain concerned that anesthesiologists will endanger patients and assume increased medicolegal risk if they do not follow the manufacturer's ASA and CDC recommended procedure.

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APA: Copy

HASHEMI, SEYED JALAL, SOLTANINEZHAD, H.A., & PARISHANI, M.. (2006). IS STORAGE OF USED STERILE PROPOFOL AT ROOM TEMPERATURE ACCOMPANIED WITH BACTERIAL CONTAMINATION?. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 24(82), 67-71. SID. https://sid.ir/paper/49642/en

Vancouver: Copy

HASHEMI SEYED JALAL, SOLTANINEZHAD H.A., PARISHANI M.. IS STORAGE OF USED STERILE PROPOFOL AT ROOM TEMPERATURE ACCOMPANIED WITH BACTERIAL CONTAMINATION?. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2006;24(82):67-71. Available from: https://sid.ir/paper/49642/en

IEEE: Copy

SEYED JALAL HASHEMI, H.A. SOLTANINEZHAD, and M. PARISHANI, “IS STORAGE OF USED STERILE PROPOFOL AT ROOM TEMPERATURE ACCOMPANIED WITH BACTERIAL CONTAMINATION?,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 24, no. 82, pp. 67–71, 2006, [Online]. Available: https://sid.ir/paper/49642/en

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