A COMPARISION OF PROPOFOL - KETAMINE COMBINATION WITH PROPOFOL - FENTANYL IN OUTPATIENT SURGERY

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SADEGHI M.; MOAPHEGH A.; VOSSUGHIAN L.

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Journal: Studies in Medical Sciences Year:2004 | Volume:15 | Issue:1 Page(s): 14-18

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Title

A COMPARISION OF PROPOFOL - KETAMINE COMBINATION WITH PROPOFOL - FENTANYL IN OUTPATIENT SURGERY

Author(s)

SADEGHI M. | MOAPHEGH A. | VOSSUGHIAN L. | Issue Writer Certificate

Keywords

KETAMINEQ3

PROPOFOLQ3

FENTANYLQ3

OUTPATIENT SURGERYQ4

Abstract

Background & Aim: General anesthesia remains the most widely used anesthetic technique for managing ambulatoy surgery. The ability to deliver a safe and cost effective general anesthetic with minimal side effects and rapid recovery is critical in OUTPATIENT SURGERY unit. Questions regarding the optimal anesthetic technique, remain to be answered. This study was designed to compare the difference between the effects of PROPOFOL-KETAMINE and PROPOFOL-fentanyl total intravenous anesthesia (TIVA); on hemodyamic, respiratory and recovery profiles. Materials & Methods: Sixty patients, ASA class I-II undergoing OUTPATIENT SURGERY were randomly assigned to one of two groups (n=30 each). After premeditation with midazolam (0/02 mg/kg), the first group received 1 µg/kg FENTANYL followed by 1mgjkg PROPOFOL; while 0/3 mg/kg ketamin replaced FENTANYL in the second group. Anesthesia was maintained with PROPOFOL infusion (50 µg/kg/min) both groups. Results: Incidence of hypotension (k: 3/3%, F: 70%), bradycardia (K: 4/3%, F: 43/3%) and mean apnea duration (k: 37/7 s, F: 184/5s) was significantly lower in the KETAMINE-propofol group (p<0.0001). Recovery, time was similar in two groups. Psychomimetic side effect was not seen in each of the groups. Discussion: TIVA with KETAMINE (as analgesic with subhypnotic dose) and PROPOFOL is comparable to the most commonly used combination of PROPOFOL-fentanyl, and may be an appropriate choice when hemodynamic stability is of great importance.

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APA: Copy

SADEGHI, M., MOAPHEGH, A., & VOSSUGHIAN, L.. (2004). A COMPARISION OF PROPOFOL - KETAMINE COMBINATION WITH PROPOFOL - FENTANYL IN OUTPATIENT SURGERY . STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 15(1), 14-18. SID. https://sid.ir/paper/63506/en

Vancouver: Copy

SADEGHI M., MOAPHEGH A., VOSSUGHIAN L.. A COMPARISION OF PROPOFOL - KETAMINE COMBINATION WITH PROPOFOL - FENTANYL IN OUTPATIENT SURGERY . STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2004;15(1):14-18. Available from: https://sid.ir/paper/63506/en

IEEE: Copy

M. SADEGHI, A. MOAPHEGH, and L. VOSSUGHIAN, “A COMPARISION OF PROPOFOL - KETAMINE COMBINATION WITH PROPOFOL - FENTANYL IN OUTPATIENT SURGERY ,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 15, no. 1, pp. 14–18, 2004, [Online]. Available: https://sid.ir/paper/63506/en

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