EFFECT OF FERROUS AND VITAMIN E ON RABBIT SERUM LIPOPROTEINS

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DASHTI GHOLAMREZA; POORMOGHADAS MASOUD; SANEI MOHAMMAD HOSEIN; HOSEINI MOHSEN; GHAYOOMI SEYED MOHAMMAD

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2011 | Volume:28 | Issue:118 Page(s): 1275-1280

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Title

EFFECT OF FERROUS AND VITAMIN E ON RABBIT SERUM LIPOPROTEINS

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Abstract

Background: Fatty streaks are the primary lesions to form atherosclerosis. Lipid per oxidation by free- radicals, plays an important role in plaque formation. Vitamin E, as a lipid in soluble vitamin, is an important antioxidant and may prevent or delay the coronary heart disease by limiting LDL oxidation. Our goal was to evaluate the effect of vitamin E and iron on blood serum lipids in male rabbits fed high – cholestrol diet.Method: Thirty white male rabbits were weighed and blood serum samples were taken for analysis of serum lipoproteins. They were randomly divided in to 5 groups each Containing 6 rabbits for 42 days. Group1 was given normal diet, Group2 fed with high cholesterol (%2) diet, Group3fed with high cholesterol diet with iron (50 kg/mg), Group4 fed with high cholesterol diet with vitamin E (50 kg/mg) , Group5 fed with high cholesterol diet with iron (50 kg/mg) and vitamin E (50 kg/mg). These groups were again weighed and blood samples were taken for analysis of serum lipoproteins after 42 days.Results: Significant difference in cholesterol, LDL, HDL, TG, VLDL, were seen before and after the experiment in all 5 groups, (p<0/000).Conclusion: The significant difference was observed between all groups in relation to the effect of iron and vitamin E on lipid metabolism. While vitamin E has a protective role in atherosclerosis, it seems that iron has a provocation role in serum lipids.

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APA: Copy

DASHTI, GHOLAMREZA, POORMOGHADAS, MASOUD, SANEI, MOHAMMAD HOSEIN, HOSEINI, MOHSEN, & GHAYOOMI, SEYED MOHAMMAD. (2011). EFFECT OF FERROUS AND VITAMIN E ON RABBIT SERUM LIPOPROTEINS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 28(118), 1275-1280. SID. https://sid.ir/paper/49662/en

Vancouver: Copy

DASHTI GHOLAMREZA, POORMOGHADAS MASOUD, SANEI MOHAMMAD HOSEIN, HOSEINI MOHSEN, GHAYOOMI SEYED MOHAMMAD. EFFECT OF FERROUS AND VITAMIN E ON RABBIT SERUM LIPOPROTEINS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;28(118):1275-1280. Available from: https://sid.ir/paper/49662/en

IEEE: Copy

GHOLAMREZA DASHTI, MASOUD POORMOGHADAS, MOHAMMAD HOSEIN SANEI, MOHSEN HOSEINI, and SEYED MOHAMMAD GHAYOOMI, “EFFECT OF FERROUS AND VITAMIN E ON RABBIT SERUM LIPOPROTEINS,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 28, no. 118, pp. 1275–1280, 2011, [Online]. Available: https://sid.ir/paper/49662/en

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