EFFECTS OF IRON AND VITAMIN E ON ENDOTHELIAL PERMEABILITY OF AORTA AND CORONARY ARTERIES IN RABBITS ON A HIGH-CHOLESTEROL DIET

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHAZAEI MAJID; KAJBAF MOHAMMAD; KAJBAF ABDOLLAH; DASHTI GHOLAMREZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Isfahan Medical School Year:2011 | Volume:29 | Issue:160 Page(s): 1473-1479

Download Full-Text

Persian Verion

View:

990

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF IRON AND VITAMIN E ON ENDOTHELIAL PERMEABILITY OF AORTA AND CORONARY ARTERIES IN RABBITS ON A HIGH-CHOLESTEROL DIET

Author(s)

KHAZAEI MAJID | KAJBAF MOHAMMAD | KAJBAF ABDOLLAH | DASHTI GHOLAMREZA | Issue Writer Certificate

Keywords

IRONQ3

VITAMIN EQ2

ENDOTHELIAL PERMEABILITYQ2

HYPERCHOLESTEROLEMIAQ3

Abstract

Background: Atherosclerosis is the leading cause of cardiovascular diseases. The relationship between enhanced ENDOTHELIAL PERMEABILITY and initiation or progression of atherosclerosis has been indicated in previous studies. The aim of this study was to investigate the effects of IRON (Fe) and VITAMIN E on ENDOTHELIAL PERMEABILITY of aorta and coronary arteries in rabbits on a high-cholesterol diet.Methods: Thirty male rabbits were randomly divided into five groups of 6, namely control, hypercholesterolemic (HC), HC +Fe (50 mg/kg), HC +vitamin E (50 mg/kg), and HC +Fe +vitamin E. After 4 weeks, blood samples were taken and ENDOTHELIAL PERMEABILITY was measured by Evans blue dye method.Findings: Administration of Fe and/or VITAMIN E improved serum lipid profile (P<0.05). Administration of Fe could not change aortic ENDOTHELIAL PERMEABILITY in hypercholesterolemic animals (P>0.05). However, VITAMIN E reduced aortic ENDOTHELIAL PERMEABILITY (P<0.05). Fe and VITAMIN E did not alter coronary artery permeability (P>0.05).Conclusion: It seems that the effects of Fe on atherosclerosis are not through the alteration of vascular permeability. However, reduced ENDOTHELIAL PERMEABILITY may be a mechanism for beneficial effects of VITAMIN E on cardiovascular system.

Cites

No record.

References

No record.

Cite

APA: Copy

KHAZAEI, MAJID, KAJBAF, MOHAMMAD, KAJBAF, ABDOLLAH, & DASHTI, GHOLAMREZA. (2011). EFFECTS OF IRON AND VITAMIN E ON ENDOTHELIAL PERMEABILITY OF AORTA AND CORONARY ARTERIES IN RABBITS ON A HIGH-CHOLESTEROL DIET. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 29(160), 1473-1479. SID. https://sid.ir/paper/49723/en

Vancouver: Copy

KHAZAEI MAJID, KAJBAF MOHAMMAD, KAJBAF ABDOLLAH, DASHTI GHOLAMREZA. EFFECTS OF IRON AND VITAMIN E ON ENDOTHELIAL PERMEABILITY OF AORTA AND CORONARY ARTERIES IN RABBITS ON A HIGH-CHOLESTEROL DIET. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;29(160):1473-1479. Available from: https://sid.ir/paper/49723/en

IEEE: Copy

MAJID KHAZAEI, MOHAMMAD KAJBAF, ABDOLLAH KAJBAF, and GHOLAMREZA DASHTI, “EFFECTS OF IRON AND VITAMIN E ON ENDOTHELIAL PERMEABILITY OF AORTA AND CORONARY ARTERIES IN RABBITS ON A HIGH-CHOLESTEROL DIET,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 29, no. 160, pp. 1473–1479, 2011, [Online]. Available: https://sid.ir/paper/49723/en

Related Journal Papers