IS VITAMIN D EFFECTIVE ON THE DISEASE ACTIVITY INDEX (DAS28) IN RHEUMATOID ARTHRITIS?

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SALESI MANSOUR; FARAJZADEGAN ZIBA; KARIMIFAR MANSOOR

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2011 | Volume:29 | Issue:129 Page(s): 180-187

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Information Journal Paper

Title

IS VITAMIN D EFFECTIVE ON THE DISEASE ACTIVITY INDEX (DAS28) IN RHEUMATOID ARTHRITIS?

Author(s)

SALESI MANSOUR | FARAJZADEGAN ZIBA | KARIMIFAR MANSOOR | Issue Writer Certificate

Keywords

VITAMIN DQ2

DISEASE ACTIVITY INDEXQ3

RHEUMATOID ARTHRITISQ2

Abstract

Background: We can prevent developing osteoporosis in RHEUMATOID ARTHRITIS (RA) patients with compounds containing calcium and VITAMIN D. In some of the studies, patients who received more VITAMIN D had better disease control. Our aim in this study was to observe whether the VITAMIN D could be effective on the RHEUMATOID ARTHRITIS disease activity or not.Methods: This study was a double blind randomized controlled clinical trial on 117 patients with RHEUMATOID ARTHRITIS. In Intervention group, in addition to drug therapy, VITAMIN D 50000 units per week were prescribed. Control group also received placebo tablets. In the end of study, results in both groups compared. Data analysis was performed by paired t-test, Student t-test and General linear Model.Findings: There were no significant differences in baseline disease severity, and DAS-28 in both groups. DAS-28 in intervention and control groups was 5.4±1.1 and 5.5±1.3, respectively (P>0.05). In both groups, all clinical and laboratory parameters after intervention were reduced. The amount of reductions in intervention group was more than the placebo group but it is not significant.Conclusion: According to this research VITAMIN D can use as an adjuvant therapy for RHEUMATOID ARTHRITIS.

Cites

THE SERUM LEVEL OF VITAMIN D AND ITS ASSOCIATION WITH DISEASE SEVERITY IN PATIENTS WITH RHEUMATOID ARTHRITIS

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APA: Copy

SALESI, MANSOUR, FARAJZADEGAN, ZIBA, & KARIMIFAR, MANSOOR. (2011). IS VITAMIN D EFFECTIVE ON THE DISEASE ACTIVITY INDEX (DAS28) IN RHEUMATOID ARTHRITIS?. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 29(129), 180-187. SID. https://sid.ir/paper/50016/en

Vancouver: Copy

SALESI MANSOUR, FARAJZADEGAN ZIBA, KARIMIFAR MANSOOR. IS VITAMIN D EFFECTIVE ON THE DISEASE ACTIVITY INDEX (DAS28) IN RHEUMATOID ARTHRITIS?. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;29(129):180-187. Available from: https://sid.ir/paper/50016/en

IEEE: Copy

MANSOUR SALESI, ZIBA FARAJZADEGAN, and MANSOOR KARIMIFAR, “IS VITAMIN D EFFECTIVE ON THE DISEASE ACTIVITY INDEX (DAS28) IN RHEUMATOID ARTHRITIS?,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 29, no. 129, pp. 180–187, 2011, [Online]. Available: https://sid.ir/paper/50016/en

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