EFFECT OF EXERCISE ON LEARNING AND MEMORY IN RATS AFTER INTRACEREBROVENTRICULAR INJECTION OF STREPTOZOTOCIN

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YOSEFI MAHDIEH; REISI PARHAM; ALAEI HOJJATALLAH; PILEHVARIAN ALI ASGHAR

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2011 | Volume:29 | Issue:151 Page(s): 1083-1090

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Title

EFFECT OF EXERCISE ON LEARNING AND MEMORY IN RATS AFTER INTRACEREBROVENTRICULAR INJECTION OF STREPTOZOTOCIN

Author(s)

YOSEFI MAHDIEH | REISI PARHAM | ALAEI HOJJATALLAH | PILEHVARIAN ALI ASGHAR | Issue Writer Certificate

Keywords

ALZHEIMER’S DISEASEQ2

TREADMILL RUNNINGQ2

EXERCISEQ2

STREPTOZOTOCINQ2

LEARNING AND MEMORYQ2

Abstract

Background: Given the positive effects of EXERCISE on the central nervous system, the aim of the present study was to evaluate the effects of TREADMILL RUNNING on LEARNING AND MEMORY in rats with induced ALZHEIMER’S DISEASE and intracerebroventricular injection of STREPTOZOTOCIN (STZ).Methods: Studied rats were divided in 4 groups: the sham-rest, the sham-exercise, the alzheimer-rest and the alzheimer-exercise. To produce rat Alzheimer’s model, STZ was infused in lateral ventricles of the brain. The EXERCISE program was TREADMILL RUNNING with 20 m/min velocity and 0o inclination for 50 min/day, for 4 weeks. For evaluation of LEARNING AND MEMORY in rats, passive avoidance learning test was used.Findings: Totally 37 rats in 4 groups were examined. The latency time for the first entrance to dark chamber one day and one week after shock was significantly shorter in Alzheimer–rest group comparing to Alzheimer–exercise and sham–rest groups.Conclusion: These results suggest that EXERCISE probably is effective in prevention and alleviation of cognitive disorders in ALZHEIMER’S DISEASE.

Cites

THE EFFECT OF AEROBIC EXERCISE ON TENDENCY TO CONSUMPTION OF MORPHINE IN MALE RAT

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APA: Copy

YOSEFI, MAHDIEH, REISI, PARHAM, ALAEI, HOJJATALLAH, & PILEHVARIAN, ALI ASGHAR. (2011). EFFECT OF EXERCISE ON LEARNING AND MEMORY IN RATS AFTER INTRACEREBROVENTRICULAR INJECTION OF STREPTOZOTOCIN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 29(151), 1083-1090. SID. https://sid.ir/paper/50276/en

Vancouver: Copy

YOSEFI MAHDIEH, REISI PARHAM, ALAEI HOJJATALLAH, PILEHVARIAN ALI ASGHAR. EFFECT OF EXERCISE ON LEARNING AND MEMORY IN RATS AFTER INTRACEREBROVENTRICULAR INJECTION OF STREPTOZOTOCIN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;29(151):1083-1090. Available from: https://sid.ir/paper/50276/en

IEEE: Copy

MAHDIEH YOSEFI, PARHAM REISI, HOJJATALLAH ALAEI, and ALI ASGHAR PILEHVARIAN, “EFFECT OF EXERCISE ON LEARNING AND MEMORY IN RATS AFTER INTRACEREBROVENTRICULAR INJECTION OF STREPTOZOTOCIN,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 29, no. 151, pp. 1083–1090, 2011, [Online]. Available: https://sid.ir/paper/50276/en

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