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Information Journal Paper

Title

GENETIC THROMBOEMBOLIC RISK FACTORS ASSOCIATED WITH DEEP VEIN THROMBOSIS IN A IRANIAN POPULATION

Pages

  795-800

Abstract

 Background: The development of venous thromboembolism is influenced by a variety of genetic and environmental RISK FACTORs. A few studies have ascertained whether thrombophilic defects are RISK FACTORs for venous thromboembolism in Middle East and IRANian populations or not.Methods: We conducted a case-control study involving 66 consecutive patients with DEEP VEIN THROMBOSIS without immobility and 66 healthy controls from the Al-Zahra Hospital in Isfahan, IRAN.Finding: The most frequent thrombophilic RISK FACTOR for DEEP VEIN THROMBOSIS was homocysteine (31/66) (OR=3.6, 95% CI= (1.66-7.84)). Anticardiolipin antibody was seen in 10.6% (OR=7.71, 95% CI= (0.99-64.55)). There were no significant differences for other RISK FACTOR such as Protein S, Protein C, Antithrombin III, Factor V leiden, and Prothrombin mutation.Conclusion: In spite of western studies, Factor V leiden and Prothrombin mutation are rare between IRANian patients. However, homocysteine and anticadiolipin anti bodies are the most frequent RISK FACTORs. Screening for Factor V leiden and Prothrombin mutation have not cost benefit and further studies with larger sample size need to detect new mutations and assess the influence of ethnicity on thrombophilia.

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    APA: Copy

    MOHAJER, HAMID, KHOSRAVI, ALI REZA, SAADATNIA, MOHAMMAD, ABDAR, MORTEZA, & AZARM, TALEB. (2011). GENETIC THROMBOEMBOLIC RISK FACTORS ASSOCIATED WITH DEEP VEIN THROMBOSIS IN A IRANIAN POPULATION. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 28(114), 795-800. SID. https://sid.ir/paper/51060/en

    Vancouver: Copy

    MOHAJER HAMID, KHOSRAVI ALI REZA, SAADATNIA MOHAMMAD, ABDAR MORTEZA, AZARM TALEB. GENETIC THROMBOEMBOLIC RISK FACTORS ASSOCIATED WITH DEEP VEIN THROMBOSIS IN A IRANIAN POPULATION. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;28(114):795-800. Available from: https://sid.ir/paper/51060/en

    IEEE: Copy

    HAMID MOHAJER, ALI REZA KHOSRAVI, MOHAMMAD SAADATNIA, MORTEZA ABDAR, and TALEB AZARM, “GENETIC THROMBOEMBOLIC RISK FACTORS ASSOCIATED WITH DEEP VEIN THROMBOSIS IN A IRANIAN POPULATION,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 28, no. 114, pp. 795–800, 2011, [Online]. Available: https://sid.ir/paper/51060/en

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