THE ANALGESIC EFFECT OF SOLENANTHUS CIRCINNATUS ROOT EXTRACT IN MALE RAT

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RANJBAR AFSANEH

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Journal Paper

Paper Information

Journal: Journal of Isfahan Medical School Year:2010 | Volume:27 | Issue:101 Page(s): 660-668

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Information Journal Paper

Title

THE ANALGESIC EFFECT OF SOLENANTHUS CIRCINNATUS ROOT EXTRACT IN MALE RAT

Author(s)

RANJBAR AFSANEH | Issue Writer Certificate

Keywords

PAINQ2

SOLENANTHUS CIRCINNATUS ROOT EXTRACTQ3

SODIUM SALICYLATEQ3

Abstract

Background: There are some evidences in Iranian traditional medicine that solenanthus circinnatus has been used for PAIN and inflammation relief. In this study, we investigated the root's hydroalcholic extract of this plant in experimental models of acute and chronic PAIN compare to analgesic effect of SODIUM SALICYLATE. Methods: Root extract were prepared using percolation method. Different doses of root extract (100, 200, 300 mg/kg i.p) and SODIUM SALICYLATE (300 mg/kg i.p) were given. The analgesic activity was assessed in experimental models of acute PAIN (Tail flick test) and chronic PAIN (used formalin test).Findings: All doses of extract and SODIUM SALICYLATE had more analgesic effect than control group in Tail flick test (P<0.05). Among mentioned extract, the dose of 300 mg/kg and SODIUM SALICYLATE had a significant antinocieptive effect to control group in both of phase formalin test (P<0.05). By comparison of the analgesic effect of SODIUM SALICYLATE and extract (at the dose of 300 mg/kg in formalin test and 200 mg/kg in Tail flick test) no significant difference was found.Conclusion: It seems that solenanthus circinnatus induces its inhibitory effect on acute and chronic PAIN.

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APA: Copy

RANJBAR, AFSANEH. (2010). THE ANALGESIC EFFECT OF SOLENANTHUS CIRCINNATUS ROOT EXTRACT IN MALE RAT. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 27(101), 660-668. SID. https://sid.ir/paper/51230/en

Vancouver: Copy

RANJBAR AFSANEH. THE ANALGESIC EFFECT OF SOLENANTHUS CIRCINNATUS ROOT EXTRACT IN MALE RAT. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2010;27(101):660-668. Available from: https://sid.ir/paper/51230/en

IEEE: Copy

AFSANEH RANJBAR, “THE ANALGESIC EFFECT OF SOLENANTHUS CIRCINNATUS ROOT EXTRACT IN MALE RAT,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 27, no. 101, pp. 660–668, 2010, [Online]. Available: https://sid.ir/paper/51230/en

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