USE OF PLEURAL ALKALINE PHOSPHATES CONTENT IN DISTINGUISHING BETWEEN EXUDATIVE AND TRANSUDATIVE EFFUSIONS

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TOWHIDI M.; VAHID S.; ROKNI YAZDI H.; EMADZADEH M.R.

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2005 | Volume:48 | Issue:87 Page(s): 63-68

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Title

USE OF PLEURAL ALKALINE PHOSPHATES CONTENT IN DISTINGUISHING BETWEEN EXUDATIVE AND TRANSUDATIVE EFFUSIONS

Author(s)

TOWHIDI M. | VAHID S. | ROKNI YAZDI H. | EMADZADEH M.R. | Issue Writer Certificate

Keywords

ALKALINE PHOSPHATASEQ2

PLEURAL EFFUSIONQ3

EXUDATESQ3

TRANSUDATESQ4

Abstract

Introduction: PLEURAL EFFUSION occurs in variety of abnormalities. Its traditional classification as TRANSUDATES or EXUDATES is useful, differentiation between TRANSUDATES and EXUDATES is the first diagnostic approach of a patient with PLEURAL EFFUSION.This study evaluates usefulness of pleural alkaline phosphates (PAP) level for distinguishing between exudative and transudative effusion and also differentiates tuberculous from malignant effusion based on the level of PAP. Material and Methods: We studied 100 patients with PLEURAL EFFUSION who referred to Ghaem Hospital; Mashhad University of Medical Sciences during a period of one year. All patients underwent diagnostic thoracentesis. The level of pleural - fluid glucose, protein, lactate dehydrogenase (LDH), cholesterol, ALKALINE PHOSPHATASE were measured. We considered the threshold level of 20 ID for PAP in differentiating TRANSUDATES from EXUDATES.Results: Among 100 patients with PLEURAL EFFUSION, 43 patients had exudative (tuberculous), 37 had exudative (malignant), and 20 had transudative effusion due to congestive heart failure (CHF). Mean value of PAP in transudative effusion, exudative tuberculous and malignant effusion were: 15.4 ± 3.5, 51.58 ± 4.47 and 79.13 ± 24.22 respectively. The difference between mean value of PAP in transudative and exudative effusion was statistically significant (p<0.001). Sensitivity, specificity and efficiency of these criteria were: 96.7 %, 86 % and 94% respectively. Conclusion: Detennination of the PAP level is useful and highly effective for distinguishing between TRANSUDATES and exsudates and should be included in biochemical analysis of PLEURAL EFFUSIONs. Our study did not show significant difference between mean value of PAP in tuberculous and malignant exsudative effusions.

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APA: Copy

TOWHIDI, M., VAHID, S., ROKNI YAZDI, H., & EMADZADEH, M.R.. (2005). USE OF PLEURAL ALKALINE PHOSPHATES CONTENT IN DISTINGUISHING BETWEEN EXUDATIVE AND TRANSUDATIVE EFFUSIONS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 48(87), 63-68. SID. https://sid.ir/paper/51534/en

Vancouver: Copy

TOWHIDI M., VAHID S., ROKNI YAZDI H., EMADZADEH M.R.. USE OF PLEURAL ALKALINE PHOSPHATES CONTENT IN DISTINGUISHING BETWEEN EXUDATIVE AND TRANSUDATIVE EFFUSIONS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;48(87):63-68. Available from: https://sid.ir/paper/51534/en

IEEE: Copy

M. TOWHIDI, S. VAHID, H. ROKNI YAZDI, and M.R. EMADZADEH, “USE OF PLEURAL ALKALINE PHOSPHATES CONTENT IN DISTINGUISHING BETWEEN EXUDATIVE AND TRANSUDATIVE EFFUSIONS,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 48, no. 87, pp. 63–68, 2005, [Online]. Available: https://sid.ir/paper/51534/en

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