EFFECT OF ORAL L-CARNITINE SUPPLEMENTATION ON HYPERLYPEDEMI IN HEMODIALYSIS CHILDREN

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KHAZAEI M.R.; DERAKHSHAN A.

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2006 | Volume:49 | Issue:91 Page(s): 49-56

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Title

EFFECT OF ORAL L-CARNITINE SUPPLEMENTATION ON HYPERLYPEDEMI IN HEMODIALYSIS CHILDREN

Author(s)

KHAZAEI M.R. | DERAKHSHAN A. | Issue Writer Certificate

Keywords

ESRDQ3

HEMODIALYSISQ3

HYPERLIPIDEMIAQ3

L- CARNITINEQ2

Abstract

Introduction: HYPERLIPIDEMIA (HL), especially when started during early childhood will increase the risk of atherosclerosis. It is also a major risk factor for allograft nephropathy and post-transplant HL, so Its treatment is highly suggested.Material and Method: In this study, the effect of oral L- CARNITINE on the lipid profile of children with end stage renal disease (ESRD) on maintenance HEMODIALYSIS (HD) after a 3-month period was evaluated.Results: Twelve out of 15 children (80%) had abnormal lipid profiles at the beginning of the study. HDL-C level increased in all of them following the treatment (P<0.001).No significant change occurred in the level of Triglyceride, Cholesterol, LDL-C, VLDL-C, but the ratio of TG/HDL-C as a major risk factor for cardiovascular disease decreased significantly (P=0.004). Conclusion: Dyslipidemia is common in HEMODIALYSIS children. In this study, short term Lcarnitine Administration (3 months) had major effect on HDL-C level increment; a longer administration may affect other components too.

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APA: Copy

KHAZAEI, M.R., & DERAKHSHAN, A.. (2006). EFFECT OF ORAL L-CARNITINE SUPPLEMENTATION ON HYPERLYPEDEMI IN HEMODIALYSIS CHILDREN. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 49(91), 49-56. SID. https://sid.ir/paper/51823/en

Vancouver: Copy

KHAZAEI M.R., DERAKHSHAN A.. EFFECT OF ORAL L-CARNITINE SUPPLEMENTATION ON HYPERLYPEDEMI IN HEMODIALYSIS CHILDREN. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2006;49(91):49-56. Available from: https://sid.ir/paper/51823/en

IEEE: Copy

M.R. KHAZAEI, and A. DERAKHSHAN, “EFFECT OF ORAL L-CARNITINE SUPPLEMENTATION ON HYPERLYPEDEMI IN HEMODIALYSIS CHILDREN,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 49, no. 91, pp. 49–56, 2006, [Online]. Available: https://sid.ir/paper/51823/en

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