HEMATOLOGIE MANIFESTATIONS IN SYSTEMIC LUPLLS ERYTHEMATOSUS

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TABARESTANI M.; HATEF M.R.; KERAMATI MOHAMMAD REZA

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2003 | Volume:45 | Issue:78 Page(s): 5-12

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Information Journal Paper

Title

HEMATOLOGIE MANIFESTATIONS IN SYSTEMIC LUPLLS ERYTHEMATOSUS

Author(s)

TABARESTANI M. | HATEF M.R. | KERAMATI MOHAMMAD REZA | Issue Writer Certificate

Keywords

SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)Q4

LUPUSQ2

LUPUS COAGULATION INHIBITORQ4

ANTI PHOSPHOLIPID SYNDROMEQ3

Abstract

The etiology of Systemic LUPUS Erythematosus (SLE) remains mystery. SLE is a multisystem disease, characterized by circulating auto antibodies and a variety of immunological abnormalities, which participate in the mediation of tissue damage. SLE is one of the rheumatological diseases that are associated with 85% hematological manifestation.We have studied major clinical and laboratory hematologic finding in 96 patients with SLE and comparison it with other countries.As the other results, M: F ratio was 1:7 and the mean diagnostic age was 21.3 years, the anemia was the most common hematologic manifestation, 79% of patients had anemia, most normochromic normocytic anemia. Leukopenia 32.3%, lymphopenia 68.8% and thrombocytopenia 15.2% were seen. 12% had coombs positive tests but we could not follow up patients for significant hemolysis. 12.5% of patients with SLE were VDRL positive, PT and APTT tests were abnormal in 5.8 and 12.1% respectively. ESR was elevated in 84.8%. The antinuclear antibodies (ANA) and antibody to double strand DNA (ds DNA) were positive in 98.8% and 83.6% respectively. LE cell was positive in 71.1% of patients with SLE.C3 and C4 were decreased in 82.1% of patients.

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APA: Copy

TABARESTANI, M., HATEF, M.R., & KERAMATI, MOHAMMAD REZA. (2003). HEMATOLOGIE MANIFESTATIONS IN SYSTEMIC LUPLLS ERYTHEMATOSUS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 45(78), 5-12. SID. https://sid.ir/paper/52206/en

Vancouver: Copy

TABARESTANI M., HATEF M.R., KERAMATI MOHAMMAD REZA. HEMATOLOGIE MANIFESTATIONS IN SYSTEMIC LUPLLS ERYTHEMATOSUS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2003;45(78):5-12. Available from: https://sid.ir/paper/52206/en

IEEE: Copy

M. TABARESTANI, M.R. HATEF, and MOHAMMAD REZA KERAMATI, “HEMATOLOGIE MANIFESTATIONS IN SYSTEMIC LUPLLS ERYTHEMATOSUS,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 45, no. 78, pp. 5–12, 2003, [Online]. Available: https://sid.ir/paper/52206/en

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