RESPONSE TO HIGH DOSE RADIOIODINE THERAPY IN 164 HYPERTHYROID PATIENTS IN DIFFERENT TIME INTERVALS

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MOUSAVI ZOHREH; ZEKOUY S.R.

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Journal: MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES Year:2003 | Volume:45 | Issue:78 Page(s): 65-70

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Title

RESPONSE TO HIGH DOSE RADIOIODINE THERAPY IN 164 HYPERTHYROID PATIENTS IN DIFFERENT TIME INTERVALS

Author(s)

MOUSAVI ZOHREH | ZEKOUY S.R. | Issue Writer Certificate

Keywords

I-131Q4

HYPERTHYROIDISMQ4

HYPOTHYROIDISMQ4

Abstract

Radioiodine therapy (RIT) is an effective, safe and easy method for treatment of HYPERTHYROIDISM. Multiple factors affect the success rate of radio- iodine therapy, however the success rate is increasing with time after RIT. This study tries to evaluate the success rate of high dose RIT (150-255 uci/gr) in different time intervals.During 3 years, 164 patients were treated with radioiodine. Questionnaires were filled for all patients including thyroid examination. Thyroid radioiodine uptakes were measured, and all patients were followed in 2-6months after radioiodine therapy and each 6 months thereafter up to 30 months. Thyroid volume measurement and clinical examination were performed for all patients in follow up visits.One hundred and thirty three females (81.1%) and 31 males (18.9%) were studied with a mean age or 44.6±14.3 yrs. Mean 1-131 doses per gram of thyroid weight was 186.6±22.5 uci/gr and mean total administered dose was 15.7±5.1 mci. Thyroid weight ranged from 20- 90 grams with a mean of 51.9 gr.Successful treatment were observed in 71.1 %, 78.7%, 83.7%, 91.4% and 95.5 in first to fifth follow ups, respectively. HYPERTHYROIDISM also was seen in 35.5%, 42.6%, 49%, 54.3% and 72.7% respectively in the first to fifth follow-ups.Also Euthroid State was seen in 34.7%, 32%, 34.7%, 37.1% and] 8.2% of patient.Conclusion: With high dose radioiodine therapy (186.6 uci/gr), 71.7% of patients was successfully treated, 2-6 months later. Every 6 months success rates were increased 5.5% averagely to reach 95.5%, 2.5 years after therapy. In the first 2 years of follow up, 34.82% of patients were in Euthroid State and the rate was decreased thereafter.

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APA: Copy

MOUSAVI, ZOHREH, & ZEKOUY, S.R.. (2003). RESPONSE TO HIGH DOSE RADIOIODINE THERAPY IN 164 HYPERTHYROID PATIENTS IN DIFFERENT TIME INTERVALS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 45(78), 65-70. SID. https://sid.ir/paper/52207/en

Vancouver: Copy

MOUSAVI ZOHREH, ZEKOUY S.R.. RESPONSE TO HIGH DOSE RADIOIODINE THERAPY IN 164 HYPERTHYROID PATIENTS IN DIFFERENT TIME INTERVALS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2003;45(78):65-70. Available from: https://sid.ir/paper/52207/en

IEEE: Copy

ZOHREH MOUSAVI, and S.R. ZEKOUY, “RESPONSE TO HIGH DOSE RADIOIODINE THERAPY IN 164 HYPERTHYROID PATIENTS IN DIFFERENT TIME INTERVALS,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 45, no. 78, pp. 65–70, 2003, [Online]. Available: https://sid.ir/paper/52207/en

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