LECTIN HISTOCHEMISTRY STUDIES OF SIALIC ACID DISTRIBUTION IN ADULT MOUSE COLON NERVOUS SYSTEM AND GLANDS

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MOFIDPOUR H.; JAFARPUR M.; GHORBANI R.

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Journal: Iranian Journal of Basic Medical Sciences Year:2003 | Volume:6 | Issue:3 (19) Page(s): 243-248

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Title

LECTIN HISTOCHEMISTRY STUDIES OF SIALIC ACID DISTRIBUTION IN ADULT MOUSE COLON NERVOUS SYSTEM AND GLANDS

Author(s)

MOFIDPOUR H. | JAFARPUR M. | GHORBANI R. | Issue Writer Certificate

Keywords

GLYCOCONJUGATESQ4

LECTIN HISTOCHEMISTERYQ4

SIALICACIEDQ4

ENTRIC NERVOUS SYSTEMQ4

COLON'S CRYPTSQ4

Abstract

Carbohydrate chains GLYCOCONJUGATES on the cell surface and extracellular matrix, particular terminal sugar, have critical role(s) in many biological functions. One terminal sugar is sialic acid, a large carbohydrate with different chemical properties. There has been little attention to distribution of these molecules in the enteric nervous system as well as other parts of the gut mall. Five paraffin section were incubated with a lectin from triticum vulgaris (WGA) in order to identify distribution of sialic acid and to some extent, N-acetylglucosamine in the adult elementary mall. Our data shows strong reaction on the enteric nervous system of the gut myenteric (Auerbach) plexus, colon crypts particularly. Their basal cell surface is stained also with this lectin. Sialic acid might facilate cell interactions between those reacted areas with their microenvironents, and as it has been well documented, these molecules may change with advanced aging and or in pathological conditions. Highly negatively charged, produced by sialic acids, they also provide biological areas for suitable molecule interaction during enteric nervous system function. Further investigation of other GLYCOCONJUGATES will be carried on in the near future.

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APA: Copy

MOFIDPOUR, H., JAFARPUR, M., & GHORBANI, R.. (2003). LECTIN HISTOCHEMISTRY STUDIES OF SIALIC ACID DISTRIBUTION IN ADULT MOUSE COLON NERVOUS SYSTEM AND GLANDS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 6(3 (19)), 243-248. SID. https://sid.ir/paper/52385/en

Vancouver: Copy

MOFIDPOUR H., JAFARPUR M., GHORBANI R.. LECTIN HISTOCHEMISTRY STUDIES OF SIALIC ACID DISTRIBUTION IN ADULT MOUSE COLON NERVOUS SYSTEM AND GLANDS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2003;6(3 (19)):243-248. Available from: https://sid.ir/paper/52385/en

IEEE: Copy

H. MOFIDPOUR, M. JAFARPUR, and R. GHORBANI, “LECTIN HISTOCHEMISTRY STUDIES OF SIALIC ACID DISTRIBUTION IN ADULT MOUSE COLON NERVOUS SYSTEM AND GLANDS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 6, no. 3 (19), pp. 243–248, 2003, [Online]. Available: https://sid.ir/paper/52385/en

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