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Information Journal Paper

Title

STUDY OF HYPERVITAMINOSIS A AND HISTOLOGICAL EFFECTS ON MICE TESTIS

Pages

  25-35

Abstract

 ObjectiveIn order to to study the therapeutic effects of high doses of vitamine A on male fertility, the histological effects on MICE TESTIS were investigated.Materials and MethodsIn this study 48 adult white male MICE in the same age were applied. The animals were divided into control and experimental groups and were kept in controlled conditions. The experimental group received the daily dosage of 25000 IU vitamine A (Retinol palmitate) intramuscularly. After the last injection, at 2, 4, and 8 day intervals, changes in testicular weight, volume, consistency and histological sections of TESTIS were studied. In addition, each time, epididymal spermatozoa were observed. Group 1 control animals received normal saline and the group 2 control animals received palmitic acid.ResultsThe results indicated that the TESTIS weight (p£0.002), volume (p£0.03), and consistency (p £0.001), decreased significantly. Also histological studies revealed a severe lossening of connective tissue in tunica albuginea and tunicavascularis. Lydig cells and somniferous tubes showed degeneration.ConclusionThese findings indicated that HYPERVITAMINOSIS A can affect the male fertility.

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    APA: Copy

    MOZAFARI JOUVIN, A., MOZAFARI JOUVIN, S., & PARIVAR, KAZEM. (2007). STUDY OF HYPERVITAMINOSIS A AND HISTOLOGICAL EFFECTS ON MICE TESTIS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 10(1 (33)), 25-35. SID. https://sid.ir/paper/52427/en

    Vancouver: Copy

    MOZAFARI JOUVIN A., MOZAFARI JOUVIN S., PARIVAR KAZEM. STUDY OF HYPERVITAMINOSIS A AND HISTOLOGICAL EFFECTS ON MICE TESTIS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2007;10(1 (33)):25-35. Available from: https://sid.ir/paper/52427/en

    IEEE: Copy

    A. MOZAFARI JOUVIN, S. MOZAFARI JOUVIN, and KAZEM PARIVAR, “STUDY OF HYPERVITAMINOSIS A AND HISTOLOGICAL EFFECTS ON MICE TESTIS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 10, no. 1 (33), pp. 25–35, 2007, [Online]. Available: https://sid.ir/paper/52427/en

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