EVALUATION OF THE SULFONAMIDES XSF AND SSF FOR ANTITUMOR ACTIVITY BY A POTATO-DISC ASSAY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BEHRAVAN J.; RARNZANI M.; RAHIMIZADEH M.; MALEKZADEH E.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Basic Medical Sciences Year:2002 | Volume:5 | Issue:3 (15) Page(s): 135-139

Download Full-Text

Persian Verion

View:

722

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF THE SULFONAMIDES XSF AND SSF FOR ANTITUMOR ACTIVITY BY A POTATO-DISC ASSAY

Author(s)

BEHRAVAN J. | RARNZANI M. | RAHIMIZADEH M. | MALEKZADEH E. | Issue Writer Certificate

Keywords

AGROBACTERIUM TUMEFACIENSQ4

POTATO DISC ASSAYQ4

ANTI-TUMOR ACTIVITYQ4

Abstract

In order to determine anti-tumor activities of two synthetic agents developed in the School of Pharmacy, MUMS, the POTATO DISC ASSAY was adopted and used in this study. Discs with specified diameter and height were cut out of potatoes and placed on plates containing agar 1.5%.A suspension of freshly grown Agrobacterium tumefactions strain B6 was inoculated on the discs, and the plates were incubated at 25°C for 30 days until crown gall tumors were appeared. After optimization of the conditions for growth and subsequent induction of crown gall tumor, vincrisrtine, a known anti-cancer drug was used to evaluate the assay. In the absence of vincristine tumors developed, while in the presence of enough concentration of the drug tumor production was inhibited. In a second step the tumor inhibitory effects of synthetic sulfonamide SSF and XSF were evaluated. Results of the test indicated ANTI-TUMOR ACTIVITY for SSF and XSF compounds with the indication that XSF was more potent as an anti-tumor agent compared to its counterpart SSF.

Cites

No record.

References

No record.

Cite

APA: Copy

BEHRAVAN, J., RARNZANI, M., RAHIMIZADEH, M., & MALEKZADEH, E.. (2002). EVALUATION OF THE SULFONAMIDES XSF AND SSF FOR ANTITUMOR ACTIVITY BY A POTATO-DISC ASSAY. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 5(3 (15)), 135-139. SID. https://sid.ir/paper/52505/en

Vancouver: Copy

BEHRAVAN J., RARNZANI M., RAHIMIZADEH M., MALEKZADEH E.. EVALUATION OF THE SULFONAMIDES XSF AND SSF FOR ANTITUMOR ACTIVITY BY A POTATO-DISC ASSAY. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2002;5(3 (15)):135-139. Available from: https://sid.ir/paper/52505/en

IEEE: Copy

J. BEHRAVAN, M. RARNZANI, M. RAHIMIZADEH, and E. MALEKZADEH, “EVALUATION OF THE SULFONAMIDES XSF AND SSF FOR ANTITUMOR ACTIVITY BY A POTATO-DISC ASSAY,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 5, no. 3 (15), pp. 135–139, 2002, [Online]. Available: https://sid.ir/paper/52505/en

Related Journal Papers