CLINICAL TRIAL OF ANTIDIABETIC EFFECT OF MORUS NIGRA LEAVE EXTRACTS

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KHAZAEI M.; HOSSEINZADEH H.; KAZEMI L.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Iranian Journal of Basic Medical Sciences Year:2002 | Volume:5 | Issue:1 (13) Page(s): 27-34

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Information Journal Paper

Title

CLINICAL TRIAL OF ANTIDIABETIC EFFECT OF MORUS NIGRA LEAVE EXTRACTS

Author(s)

KHAZAEI M. | HOSSEINZADEH H. | KAZEMI L. | Issue Writer Certificate

Keywords

MORUS NIGRAQ4

DIABETES MELLITUSQ3

ANTIHYPERGLYCEMICQ4

CLINICAL TRIALQ3

Abstract

In an open and cross over trial, the antidiabetic effect of the leaves of MORUS NIGRA was studied. Fifty patients with the non insulin dependent DIABETES MELLITUS (NIDDM) (38 women and 12 men) between 25 and 60 years old were studied. The fasting blood sugars (FBS) were between 150 mg/dl to 250 mg/dl. Microbial control tests were done for the extracts. Three groups of patients (10 people in each group) took decoction extracts (5, 10 and 15 percent) once a day. The treatments lasted for one week. Before and after treatment, the following parameters were determined: FBS, blood pressure and weight. At each visit (before and after treatment) a questionnaire about side effects and associated symptoms were completed. The extracts did not reduce FBS after 7 days administration. Glibenclamide (2.5 mg/day) reduced FBS after 7 days. Adding the extract to glibenclamide group, did not increase the antidiabetic effect of this drug. In this study neuropathy and symptoms of diabetes were improved by the extracts. It is possible these extracts act like biguanides in reduction diabetic symptoms and eleminate neuropathy like analgesic or anesthetic drugs.

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APA: Copy

KHAZAEI, M., HOSSEINZADEH, H., & KAZEMI, L.. (2002). CLINICAL TRIAL OF ANTIDIABETIC EFFECT OF MORUS NIGRA LEAVE EXTRACTS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 5(1 (13)), 27-34. SID. https://sid.ir/paper/52510/en

Vancouver: Copy

KHAZAEI M., HOSSEINZADEH H., KAZEMI L.. CLINICAL TRIAL OF ANTIDIABETIC EFFECT OF MORUS NIGRA LEAVE EXTRACTS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2002;5(1 (13)):27-34. Available from: https://sid.ir/paper/52510/en

IEEE: Copy

M. KHAZAEI, H. HOSSEINZADEH, and L. KAZEMI, “CLINICAL TRIAL OF ANTIDIABETIC EFFECT OF MORUS NIGRA LEAVE EXTRACTS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 5, no. 1 (13), pp. 27–34, 2002, [Online]. Available: https://sid.ir/paper/52510/en

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