THE EEFFECTS OF SILVER NANOPARTICLES ALONE AND IN COMBINATION WITH IMIPENEM ON INHIBITION OF PSEUDOMONAS AERUGINOSA BIOFILM FORMATION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAMEZANI ALI AKBARI KHADIJEH; ABDI ALI AHYA; SEIFALI MAHVASH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2016 | Volume:21 | Issue:72 Page(s): 1-13

Download Full-Text

Persian Verion

View:

787

Download:

Cites:

Information Journal Paper

Title

THE EEFFECTS OF SILVER NANOPARTICLES ALONE AND IN COMBINATION WITH IMIPENEM ON INHIBITION OF PSEUDOMONAS AERUGINOSA BIOFILM FORMATION

Author(s)

RAMEZANI ALI AKBARI KHADIJEH | ABDI ALI AHYA | SEIFALI MAHVASH | Issue Writer Certificate

Keywords

PSEUDOMONAS AERUGINOSAQ2

IMIPENEMQ2

BIOFILMQ1

SILVER NANOPARTICLESQ1

Abstract

Background and objective: PSEUDOMONAS AERUGINOSA is an important opportunistic, forming BIOFILM pathogen. The its BIOFILM has created the effective barrier against penetration of antimicrobial agents, in result the drug resistance is increased 1000 times in BIOFILM cells versus planktonic cells. But nanomaterial are good candidates since their use does not lead to the development of resistance. In current study, the ant BIOFILM effects of SILVER NANOPARTICLES alone and in combination with IMIPENEM on BIOFILM producing P. aeruginosa was investigated.Materials and methods: 60 isolates of P. aeruginosa were collected from shahid Motahari burn hospital, Mehr burn hospital and shahid Rajai Cardiovascular hospital in Tehran. 20 strong BIOFILM-producing isolates were selected to investigate the ant BIOFILM effects of SILVER NANOPARTICLES by microdilution plate technique. The combined effects of SILVER NANOPARTICLES and IMIPENEM was determined through Checkerboard dilution technique on 10 strong BIOFILM-producing isolates.Results: In the presence of a dilution series 0.4-50mg /ml SILVER NANOPARTICLES, reduction of BIOFILM biomass was different among the studied 20 isolates and was seen the biomass reduction 4-95% in 14 isolates. The effects of IMIPENEM in combination with SILVER NANOPARTICLES on the inhibition of BIOFILM formation showed synergistic relationships (SFIC ≤0.5) in majority of the isolates.Conclusion: This study suggests that the SILVER NANOPARTICLES can be a promising candidate to inhibit the formation of P. aeruginosa BIOFILM .Moreover SILVER NANOPARTICLES in combination with antibiotics such as IMIPENEM can reduce dramatically P. aeruginosa BIOFILM formation on surfaces.

Cites

No record.

References

No record.

Cite

APA: Copy

RAMEZANI ALI AKBARI, KHADIJEH, ABDI ALI, AHYA, & SEIFALI, MAHVASH. (2016). THE EEFFECTS OF SILVER NANOPARTICLES ALONE AND IN COMBINATION WITH IMIPENEM ON INHIBITION OF PSEUDOMONAS AERUGINOSA BIOFILM FORMATION. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 21(72), 1-13. SID. https://sid.ir/paper/52808/en

Vancouver: Copy

RAMEZANI ALI AKBARI KHADIJEH, ABDI ALI AHYA, SEIFALI MAHVASH. THE EEFFECTS OF SILVER NANOPARTICLES ALONE AND IN COMBINATION WITH IMIPENEM ON INHIBITION OF PSEUDOMONAS AERUGINOSA BIOFILM FORMATION. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2016;21(72):1-13. Available from: https://sid.ir/paper/52808/en

IEEE: Copy

KHADIJEH RAMEZANI ALI AKBARI, AHYA ABDI ALI, and MAHVASH SEIFALI, “THE EEFFECTS OF SILVER NANOPARTICLES ALONE AND IN COMBINATION WITH IMIPENEM ON INHIBITION OF PSEUDOMONAS AERUGINOSA BIOFILM FORMATION,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 21, no. 72, pp. 1–13, 2016, [Online]. Available: https://sid.ir/paper/52808/en

Related Journal Papers