SURVEYING THE PREVALENCE OF ANTIPHOPHOLIPID ANTIBODY IN WOMEN WITH RECURRENT PREGNANCY LOSS REFERRING TO SHAHID BEHESHTI HOSPITALS, 1996-98

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HAJFATH ALI A.; KARIMIAN N.; ELMI GHORVI E.; TAHER POUR A.; VALAEI NASER; ESFANDIARI N.; BEH NIA H.

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Journal: Researcher Bulletin of Medical Sciences Year:2001 | Volume:6 | Issue:1 (21) Page(s): 5-11

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Title

SURVEYING THE PREVALENCE OF ANTIPHOPHOLIPID ANTIBODY IN WOMEN WITH RECURRENT PREGNANCY LOSS REFERRING TO SHAHID BEHESHTI HOSPITALS, 1996-98

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Keywords

RECURRENT PREGNANCY LOSS

ABORTION

INTRAUTERINE DEATH

ANTIPHOPHOLIPID ANTIBODY

Abstract

Background: Fetal loss and recurrent ABORTION are among the most common disease, which has known side effects. Regarding the etiologic importance and previous reports of antiphospholipid antibody role in recurrent ABORTION and fetal loss, and also controversial reports, this study has been carried out to determine the prevalence of ANTIPHOPHOLIPID ANTIBODY in women with RECURRENT PREGNANCY LOSS referring to Shahid Beheshti hospitals, 1996-98. Materials and methods: This descriptive study had been carried out on 210 women with definite diagnosis of recurrent ABORTION or fetal loss. They have been asked to refer to a determined laboratory, where their demographic and other useful data have been collected. Then, 7 cc bloods have been taken for VDRL and ANTIPHOPHOLIPID ANTIBODY studies and another 3 cc of citrated blood for aPTT. In the meanwhile, 40 matched women with at least 2 successful deliveries and negative history of fetal loss or recurrent ABORTION have been studied. Normal individuals were those who have GPL of less than 10, then, the prevalence of ANTIPHOPHOLIPID ANTIBODY has been determined in our society. Results: 210 women who met our criteria entered our study. The mean age was 28.9+4.5, the number of pregnancies was 3.3+ 1.4 (2-10) and the number of ABORTIONs was 2.6+ 1.3 (max. of 10). The antibody level was below l0 in forty normal and matched women. 44 women have been reported to have abnormal antibody level, so the prevalence of ANTIPHOPHOLIPID ANTIBODY was 21%, however, the overall prevalence in the society has been estimated to be between 16 and 26%. Results have implied that increasing ANTIPHOPHOLIPID ANTIBODY level is associated with increasing pregnancy loss. Conclusion: The prevalence of ANTIPHOPHOLIPID ANTIBODY in our country is the same as other countries. Analytic studies are strongly recommended to determine the position of this antibody in fetal loss and spontaneous ABORTION, however, experimental studies are required to find out suitable and effective treatment.

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APA: Copy

HAJFATH ALI, A., KARIMIAN, N., ELMI GHORVI, E., TAHER POUR, A., VALAEI, NASER, ESFANDIARI, N., & BEH NIA, H.. (2001). SURVEYING THE PREVALENCE OF ANTIPHOPHOLIPID ANTIBODY IN WOMEN WITH RECURRENT PREGNANCY LOSS REFERRING TO SHAHID BEHESHTI HOSPITALS, 1996-98. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 6(1 (21)), 5-11. SID. https://sid.ir/paper/528319/en

Vancouver: Copy

HAJFATH ALI A., KARIMIAN N., ELMI GHORVI E., TAHER POUR A., VALAEI NASER, ESFANDIARI N., BEH NIA H.. SURVEYING THE PREVALENCE OF ANTIPHOPHOLIPID ANTIBODY IN WOMEN WITH RECURRENT PREGNANCY LOSS REFERRING TO SHAHID BEHESHTI HOSPITALS, 1996-98. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2001;6(1 (21)):5-11. Available from: https://sid.ir/paper/528319/en

IEEE: Copy

A. HAJFATH ALI, N. KARIMIAN, E. ELMI GHORVI, A. TAHER POUR, NASER VALAEI, N. ESFANDIARI, and H. BEH NIA, “SURVEYING THE PREVALENCE OF ANTIPHOPHOLIPID ANTIBODY IN WOMEN WITH RECURRENT PREGNANCY LOSS REFERRING TO SHAHID BEHESHTI HOSPITALS, 1996-98,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 6, no. 1 (21), pp. 5–11, 2001, [Online]. Available: https://sid.ir/paper/528319/en

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