NEUROMUSCULAR RESPONSE OF THE HALLUCIS MUSCLE TO IONTOPHORESIS OF EPINEPHRINE IN HEALTHY MEN

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TALEBIAN S.; HAJIZADEH S.; FATOLLAHI I.; OLYAIE GH.R.

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Journal Paper

Paper Information

Journal: KOWSAR MEDICAL JOURNAL Year:2001 | Volume:6 | Issue:part 3 Page(s): 165-174

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Title

NEUROMUSCULAR RESPONSE OF THE HALLUCIS MUSCLE TO IONTOPHORESIS OF EPINEPHRINE IN HEALTHY MEN

Author(s)

TALEBIAN S. | HAJIZADEH S. | FATOLLAHI I. | OLYAIE GH.R. | Issue Writer Certificate

Keywords

EPINEPHRINE

ELECTROTHERAPY

IONTOPHORESIS

MUSCLE ACTION POTENTIAL

NEUROMUSCULAR JUNCTION.

Abstract

The purpose of this study was to investigate the iontophoretic effect of EPINEPHRINE on the compound MUSCLE ACTION POTENTIAL (CMAP) and physiological aspects of nerves and muscle, to increase the function of physical therapy. Twenty healthy men ranging 20-30 years were divided in two groups (iontophorsis and direct current). EPINEPHRINE solution (1 mg/ml) was used for IONTOPHORESIS and normal saline for direct current. After recording CMAP, IONTOPHORESIS and direct current were applied for each group.(50 mA. min) by placing an active electrode on CMAPs were examined at 1, 5, 10 and 15 minutes after the IONTOPHORESIS and direct current stimulation and then compared with an average of 5 recordings before application of iontophpresis and direct current. The results of this study show that IONTOPHORESIS of EPINEPHRINE increases after amplitude 5, 10, and 15 minutes (p<0.05) and increases positive peak, duration and rising time after 1,5,10, and 15 minutes (p<0.05). Increased repolarization in the first minute after IONTOPHORESIS was significant (P<0.05). Direct current increases the duration, rising time, propagation of depolarization and repolarization time at 1, 5, 10 and 15 minutes (P<0.05). The slope of propagation after iotophoresis increase at 10 minutes (P<0.05) where as direct current reduces the slopes of rising, propagation, and repolarization of CMAPs at 1,5,10 and 15 minutes (P<0.05). These findings indicate that IONTOPHORESIS of EPINEPHRINE effect the NEUROMUSCULAR JUNCTION.to increase muscle fibers involvement where as direct current stimulation with hyperpolarization reduce suitable activities of muscle fibers.

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APA: Copy

TALEBIAN, S., HAJIZADEH, S., FATOLLAHI, I., & OLYAIE, GH.R.. (2001). NEUROMUSCULAR RESPONSE OF THE HALLUCIS MUSCLE TO IONTOPHORESIS OF EPINEPHRINE IN HEALTHY MEN. KOWSAR MEDICAL JOURNAL, 6(part 3), 165-174. SID. https://sid.ir/paper/528410/en

Vancouver: Copy

TALEBIAN S., HAJIZADEH S., FATOLLAHI I., OLYAIE GH.R.. NEUROMUSCULAR RESPONSE OF THE HALLUCIS MUSCLE TO IONTOPHORESIS OF EPINEPHRINE IN HEALTHY MEN. KOWSAR MEDICAL JOURNAL[Internet]. 2001;6(part 3):165-174. Available from: https://sid.ir/paper/528410/en

IEEE: Copy

S. TALEBIAN, S. HAJIZADEH, I. FATOLLAHI, and GH.R. OLYAIE, “NEUROMUSCULAR RESPONSE OF THE HALLUCIS MUSCLE TO IONTOPHORESIS OF EPINEPHRINE IN HEALTHY MEN,” KOWSAR MEDICAL JOURNAL, vol. 6, no. part 3, pp. 165–174, 2001, [Online]. Available: https://sid.ir/paper/528410/en

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