ADVANCES IN INNATE IMMUNITY: THE ROLE OF TOLL-LIKE RECEPTOR SIGNALING IN HUMAN DISEASE

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HO J.; LI Y.; HIRSCHFELD A.; MANSOURI D.; TURVEY S.

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Journal: TANAFFOS Year:2004 | Volume:3 | Issue:11 Page(s): 7-14

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Title

ADVANCES IN INNATE IMMUNITY: THE ROLE OF TOLL-LIKE RECEPTOR SIGNALING IN HUMAN DISEASE

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Abstract

The field of innate immunity has undergone an explosion over the past decade with the discovery of receptor families that are instrumental in the first line recognition of microbes by hosts, and the regulation of innate and adaptive immune responses. In particular, the Toll-like receptor (TLR) family acts to sense foreign microbial products, and initiates a cascade of events that include the secretion of proinflammatory cytokines, the maturation of dendritic cells, and the activation of B- and T- cells. Given their pivotal role in host defense, it is not surprising that recent studies have identified a role for TLR function in several important human diseases, including sepsis, immunodeficiencies, atherosclerosis and allergies.

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APA: Copy

HO, J., LI, Y., HIRSCHFELD, A., MANSOURI, D., & TURVEY, S.. (2004). ADVANCES IN INNATE IMMUNITY: THE ROLE OF TOLL-LIKE RECEPTOR SIGNALING IN HUMAN DISEASE. TANAFFOS, 3(11), 7-14. SID. https://sid.ir/paper/528798/en

Vancouver: Copy

HO J., LI Y., HIRSCHFELD A., MANSOURI D., TURVEY S.. ADVANCES IN INNATE IMMUNITY: THE ROLE OF TOLL-LIKE RECEPTOR SIGNALING IN HUMAN DISEASE. TANAFFOS[Internet]. 2004;3(11):7-14. Available from: https://sid.ir/paper/528798/en

IEEE: Copy

J. HO, Y. LI, A. HIRSCHFELD, D. MANSOURI, and S. TURVEY, “ADVANCES IN INNATE IMMUNITY: THE ROLE OF TOLL-LIKE RECEPTOR SIGNALING IN HUMAN DISEASE,” TANAFFOS, vol. 3, no. 11, pp. 7–14, 2004, [Online]. Available: https://sid.ir/paper/528798/en

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