PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS

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RAMEZANI AMITIS; GACHKAR L.; ESLAMIFAR A.; HAMKAR R.; BANIFAZL M.; YADEGARI D.; JALILVAND S.; ADIBI L.; SALIMI N.; NAGHILI B.; KHOUSHBATEN M.; VELAYATI A.A.

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Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2007 | Volume:12 | Issue:37 Page(s): 41-46

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Title

PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS

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Keywords

HEPATITIS G VIRUS (HGV)Q3

BLOOD DONORQ3

HEPATITIS B VIRUS CO-INFECTIONQ3

Abstract

Background and objective: Frequency of Hepatitis G virus exposure in BLOOD DONORs varies between 2.5% in Japan to 24.2% in Poland. Therefore there is a geographic difference in distribution of Hepatitis G virus (HGV) in the world. We aimed to determine the frequency of HGV exposure in Iranian BLOOD DONORs.Material and methods: Blood samples from 478 Iranian volunteer BLOOD DONORs were tested. Positive anti-E2 samples were tested for HGV RNA by RT PCR using primers derived from the NS5A region of the viral genome.Results: From 478 donors enrolled in our study, 5(1%) of them were positive for anti-E2. Co-infection of HGV with hepatitis B virus (HBV) was seen in 33.3% but we didn't find HGV and HCV co-infection in our subjects. HGV RNA wasn't observed in 5 anti-E2 positive subjects. We didn't find HGV viremia and antibody at the same time.Conclusion: Regarding to low frequency of HGV exposure in BLOOD DONORs it doesn't seem that supervision and screening of BLOOD DONORs will be necessary. We didn't observe co-infection of HGV with HCV in our subjects, supporting that although parenteral route is the most effective way, other routes such as sexual contact and intra familial contact may also play role in HGV transmission.

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APA: Copy

RAMEZANI, AMITIS, GACHKAR, L., ESLAMIFAR, A., HAMKAR, R., BANIFAZL, M., YADEGARI, D., JALILVAND, S., ADIBI, L., SALIMI, N., NAGHILI, B., KHOUSHBATEN, M., & VELAYATI, A.A.. (2007). PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 12(37), 41-46. SID. https://sid.ir/paper/52958/en

Vancouver: Copy

RAMEZANI AMITIS, GACHKAR L., ESLAMIFAR A., HAMKAR R., BANIFAZL M., YADEGARI D., JALILVAND S., ADIBI L., SALIMI N., NAGHILI B., KHOUSHBATEN M., VELAYATI A.A.. PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2007;12(37):41-46. Available from: https://sid.ir/paper/52958/en

IEEE: Copy

AMITIS RAMEZANI, L. GACHKAR, A. ESLAMIFAR, R. HAMKAR, M. BANIFAZL, D. YADEGARI, S. JALILVAND, L. ADIBI, N. SALIMI, B. NAGHILI, M. KHOUSHBATEN, and A.A. VELAYATI, “PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 12, no. 37, pp. 41–46, 2007, [Online]. Available: https://sid.ir/paper/52958/en

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