EFFICACY OF CRYOANALGESIA VERSUS BUPIVACAINE AS TWO METHODS OF INTERCOSTAL NERVE BLOCKADE ON POST-THORACOTOMY PAIN RELIEF: A HUMAN PROSPECTIVE RANDOMIZED CLINICAL TRIAL

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FAZELI SH.; TABATABAEI A.; HASHEMI M.; AMINI HARANDI A.

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Paper Information

Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2004 | Volume:9 | Issue:6 Page(s): 50-54

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Title

EFFICACY OF CRYOANALGESIA VERSUS BUPIVACAINE AS TWO METHODS OF INTERCOSTAL NERVE BLOCKADE ON POST-THORACOTOMY PAIN RELIEF: A HUMAN PROSPECTIVE RANDOMIZED CLINICAL TRIAL

Author(s)

FAZELI SH. | TABATABAEI A. | HASHEMI M. | AMINI HARANDI A. | Issue Writer Certificate

Keywords

CRYOANALGESIA

BUPIVACAINE

BLOCKADE

POSTOPERATION PAIN

THORACOTOMY

OSTEROLATERAL

INTERCOSTAL NERVES

NERVE BLOCK

ANALGESIA

Abstract

Background: Pain following posterolateral THORACOTOMY, is recognized as a major cause of morbidity and mortality. Various methods have been used for the treatment of post-thoracotomy pain, however, the treatment of post-thoracotomy pain remains controversial. The aim of this study was to compare the efficacy of BUPIVACAINE versus CRYOANALGESIA for local intercostal nerve BLOCKADE on post-thoracotomy pain relief.Methods: In a randomized clinical trial, eighty patients who were scheduled to undergo posterolateral THORACOTOMY were selected and classified, randomly, into two groups. Group A underwent intercostal nerve BLOCKADE with BUPIVACAINE every 8 hours after surgery for three days. In group B, two nerves-upper and lower of incision level was freeze by Cryoprobe.Postoperative pain was assessed by 0-10 cm visual Analogue Scale (VAS) every 8 hours and then, after one hour, both groups were received intravenous morphine according to their needs.Results: Mean and standard deviation (Mean±SD) of pain level were 4.70±2.38 in group A and 4.87±2.25 in group B.The t-test showed no statistically significant differences between two groups (t=1.08, P=0.28). Morphine consumption was 5.35±3.17mg in group A and 5.30±3.20 mg in group B; Also there were no statistically significant differences between two groups (t=1.25, P=0.21).Conclusion: CRYOANALGESIA and BUPIVACAINE showed equivalent analgesic effect on poster lateral THORACOTOMY pain reduction. We suggest CRYOANALGESIA as an easy-to-use technique, but for routine application, further studies with long-term follow up and more cases are recommended.

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APA: Copy

FAZELI, SH., TABATABAEI, A., HASHEMI, M., & AMINI HARANDI, A.. (2004). EFFICACY OF CRYOANALGESIA VERSUS BUPIVACAINE AS TWO METHODS OF INTERCOSTAL NERVE BLOCKADE ON POST-THORACOTOMY PAIN RELIEF: A HUMAN PROSPECTIVE RANDOMIZED CLINICAL TRIAL. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 9(6), 50-54. SID. https://sid.ir/paper/530769/en

Vancouver: Copy

FAZELI SH., TABATABAEI A., HASHEMI M., AMINI HARANDI A.. EFFICACY OF CRYOANALGESIA VERSUS BUPIVACAINE AS TWO METHODS OF INTERCOSTAL NERVE BLOCKADE ON POST-THORACOTOMY PAIN RELIEF: A HUMAN PROSPECTIVE RANDOMIZED CLINICAL TRIAL. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2004;9(6):50-54. Available from: https://sid.ir/paper/530769/en

IEEE: Copy

SH. FAZELI, A. TABATABAEI, M. HASHEMI, and A. AMINI HARANDI, “EFFICACY OF CRYOANALGESIA VERSUS BUPIVACAINE AS TWO METHODS OF INTERCOSTAL NERVE BLOCKADE ON POST-THORACOTOMY PAIN RELIEF: A HUMAN PROSPECTIVE RANDOMIZED CLINICAL TRIAL,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 9, no. 6, pp. 50–54, 2004, [Online]. Available: https://sid.ir/paper/530769/en

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