ANTICONVULSANT EFFECTS OF CUMINIUM CYMINUM L. SEEDS EXTRACTS AND ESSENTIAL OIL IN MICE

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HOSSEINZADEH H.; RAMEZANI MOHAMMAD; FADISHEI M.; BASIRAT M.

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Journal Paper

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Journal: Journal of Medicinal Plants Year:2002 | Volume:1 | Issue:2 Page(s): 0-0

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Title

ANTICONVULSANT EFFECTS OF CUMINIUM CYMINUM L. SEEDS EXTRACTS AND ESSENTIAL OIL IN MICE

Author(s)

HOSSEINZADEH H. | RAMEZANI MOHAMMAD | FADISHEI M. | BASIRAT M. | Issue Writer Certificate

Keywords

CUMINUM CYMINUM

CONVULSION

MEDICINAL PLANTS

Abstract

The anticonvulsant effects of aqueous and ethanolic extracts as well as essential oil of CUMINUM CYMINUM L. seeds were studied in mice. In pentylenetetrazole test, the essential oil and the extracts of seeds prolonged the onset time of tonic CONVULSION, but failed to produce complete protection against mortality. In this test, the anticonvulsant efficacy of the aqueous (2.8 g/kg) and ethanolic (5 g/kg) extracts was similar as phenobarbital at a dose of 20 mg/kg. In maximal electroshock test, the aqueous (4 g/kg) and ethanolic (5 g/kg) extracts as well as essential oil (0.35 g/kg) decreased the duration of tonic seizures by 37.6%, 68.2% and 59.1%, respectively. These results indicate that the extracts and essential oil of CUMINUM CYMINUM seeds may have efficacy in petit mal and grand mal seizures.

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APA: Copy

HOSSEINZADEH, H., RAMEZANI, MOHAMMAD, FADISHEI, M., & BASIRAT, M.. (2002). ANTICONVULSANT EFFECTS OF CUMINIUM CYMINUM L. SEEDS EXTRACTS AND ESSENTIAL OIL IN MICE. JOURNAL OF MEDICINAL PLANTS, 1(2), 0-0. SID. https://sid.ir/paper/532186/en

Vancouver: Copy

HOSSEINZADEH H., RAMEZANI MOHAMMAD, FADISHEI M., BASIRAT M.. ANTICONVULSANT EFFECTS OF CUMINIUM CYMINUM L. SEEDS EXTRACTS AND ESSENTIAL OIL IN MICE. JOURNAL OF MEDICINAL PLANTS[Internet]. 2002;1(2):0-0. Available from: https://sid.ir/paper/532186/en

IEEE: Copy

H. HOSSEINZADEH, MOHAMMAD RAMEZANI, M. FADISHEI, and M. BASIRAT, “ANTICONVULSANT EFFECTS OF CUMINIUM CYMINUM L. SEEDS EXTRACTS AND ESSENTIAL OIL IN MICE,” JOURNAL OF MEDICINAL PLANTS, vol. 1, no. 2, pp. 0–0, 2002, [Online]. Available: https://sid.ir/paper/532186/en

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