TREATMENT OF RESECTABLE DISTAL RECTAL CANCER WITH PREOPERATIVE CHEMORADIATION AND SPHINCTER SAVING SURGERY

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OMRANIPOUR R.; ABASAHL A.A.GH.

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Journal: Tehran University Medical Journal Year:2000 | Volume:58 | Issue:1 Page(s): 26-31

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Title

TREATMENT OF RESECTABLE DISTAL RECTAL CANCER WITH PREOPERATIVE CHEMORADIATION AND SPHINCTER SAVING SURGERY

Author(s)

OMRANIPOUR R. | ABASAHL A.A.GH. | Issue Writer Certificate

Keywords

RECTAL CANCER

PREOPERATIVE CHEMORADIOTHERAPY

SPHINCTER SAVING SURGERY

COMPLICATIONS

Abstract

To determine if preoperative combined chemoradiation therapy increase sphincter preservation in the treatment of low-lying RECTAL CANCER, 15 patients were treated with preoperative chemoradiation: 5FU plus mitomycin C plus 4500-5000 Rad concurrent external beam radiotherapy between Jan 1997 and Jan 1999. There were 10 men and 5 women (mean age: 49y) with the diagnosis of invasive resectable primary adenocarcinoma of distal rectum limited to pelvis. Median tumor distance from anal verge was 3.3 cm (range 0-5 cm) and half of the patients were absolute candidate for abdominoperineal resection. After 4-6 weeks, all patients were undergone proctectomy and eventually sphincter preservation surgery was done on 9 patients with colonal anastomosis. Function of sphincter was excellent in 6 of them (66%) and good in 3 patients (33%). There was no case of incontinence.Complications of surgery were minimal: one case of stricture (10%) and one case of partial rupture of anastomosis (10%). Complete pathologic response was achieved on one patient (6.6%) and combined preoperative chemoradiation has changed the plan of surgery from abdominoperineal resection to sphincter saving in 69.2% of patients.

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APA: Copy

OMRANIPOUR, R., & ABASAHL, A.A.GH.. (2000). TREATMENT OF RESECTABLE DISTAL RECTAL CANCER WITH PREOPERATIVE CHEMORADIATION AND SPHINCTER SAVING SURGERY. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 58(1), 26-31. SID. https://sid.ir/paper/533281/en

Vancouver: Copy

OMRANIPOUR R., ABASAHL A.A.GH.. TREATMENT OF RESECTABLE DISTAL RECTAL CANCER WITH PREOPERATIVE CHEMORADIATION AND SPHINCTER SAVING SURGERY. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2000;58(1):26-31. Available from: https://sid.ir/paper/533281/en

IEEE: Copy

R. OMRANIPOUR, and A.A.GH. ABASAHL, “TREATMENT OF RESECTABLE DISTAL RECTAL CANCER WITH PREOPERATIVE CHEMORADIATION AND SPHINCTER SAVING SURGERY,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 58, no. 1, pp. 26–31, 2000, [Online]. Available: https://sid.ir/paper/533281/en

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