RELATIONSHIP BETWEEN VITAMIN D DEFICIENCY AND GESTATIONAL DIABETES MELLITUS

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HOSSEINNEZHAD ARASH; MAGHBOOLI J.; ARZAGHI M.; SHAFAEI A.R.; RAHMANI M.; ARDESHIR LARIJANI MOHAMMAD BAGHER

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Journal: Iranian Journal of Diabetes and Metabolism Year:2006 | Volume:5 | Issue:3 Page(s): 227-234

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Title

RELATIONSHIP BETWEEN VITAMIN D DEFICIENCY AND GESTATIONAL DIABETES MELLITUS

Author(s)

Keywords

GDMQ2

VITAMIN DQ2

INSULIN RESISTANCEQ2

Abstract

Background: Although there is increasing evidences that VITAMIN D is related to the occurrence of diabetes mellitus, its relation to glucose metabolism in pregnancy is not well studied. This study investigated 25-hydroxyvitamin D deficiency status in GDM pregnant women. Methods: As a cross sectional study we recruited 741 pregnant women referred to five university educating hospital clinics. The universal screening was performed with a GCT-50g and those with plasma glucose level ≥130mg/dl, were diagnosed as GDM, if they had an impaired GTT-100g based on Carpenter and Coustan criteria. The levels of insulin were studied during OGTT-100g. Serum concentrations of 25-hydroxy VITAMIN D were measured too. Results: Univeriate analysis revealed that 25 (OH) vit D concentrations were positively correlated with HOMA and ISOGTT index. Subjects with hypovitaminosis D (<12.5nmol/dl) had greater prevalence of GDM than others. Conclusion: The results reveal a positive association between 25(OH) vit D concentrations and insulin sensitivity. Vit D deficiency is more prevalent in patients with GDM than normal pregnant women, So vit D supplementation may control glucose levels and improves outcome of pregnancy.

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References

SYMPTOM AND CLINICAL FEATURES IN PREGNANT WOMEN WITH DIFFERENT DEGREE OF CARBOHYDRATE INTOLERANCE

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APA: Copy

HOSSEINNEZHAD, ARASH, MAGHBOOLI, J., ARZAGHI, M., SHAFAEI, A.R., RAHMANI, M., & ARDESHIR LARIJANI, MOHAMMAD BAGHER. (2006). RELATIONSHIP BETWEEN VITAMIN D DEFICIENCY AND GESTATIONAL DIABETES MELLITUS. JOURNAL OF DIABETES AND METABOLIC DISORDERS, 5(3), 227-234. SID. https://sid.ir/paper/53912/en

Vancouver: Copy

HOSSEINNEZHAD ARASH, MAGHBOOLI J., ARZAGHI M., SHAFAEI A.R., RAHMANI M., ARDESHIR LARIJANI MOHAMMAD BAGHER. RELATIONSHIP BETWEEN VITAMIN D DEFICIENCY AND GESTATIONAL DIABETES MELLITUS. JOURNAL OF DIABETES AND METABOLIC DISORDERS[Internet]. 2006;5(3):227-234. Available from: https://sid.ir/paper/53912/en

IEEE: Copy

ARASH HOSSEINNEZHAD, J. MAGHBOOLI, M. ARZAGHI, A.R. SHAFAEI, M. RAHMANI, and MOHAMMAD BAGHER ARDESHIR LARIJANI, “RELATIONSHIP BETWEEN VITAMIN D DEFICIENCY AND GESTATIONAL DIABETES MELLITUS,” JOURNAL OF DIABETES AND METABOLIC DISORDERS, vol. 5, no. 3, pp. 227–234, 2006, [Online]. Available: https://sid.ir/paper/53912/en

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