THE EVALUATION OF THE EFFECT OF VITAMIN D ON INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS

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TALAEI A.; MOHAMMADI K.M.; ADGI Z.

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Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2011 | Volume:14 | Issue:5 (58) Page(s): 79-84

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Title

THE EVALUATION OF THE EFFECT OF VITAMIN D ON INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS

Author(s)

TALAEI A. | MOHAMMADI K.M. | ADGI Z. | Issue Writer Certificate

Keywords

DIABETESQ2

GLUCOSEQ2

HOMA-IRQ2

INSULINQ2

VITAMIN DQ2

Abstract

Background: Different studies have shown that VITAMIN D may play a functional role in INSULIN secretion and sensitivity. This study evaluates the effect of VITAMIN D on INSULIN resistance.Materials and Methods: This clinical trial was done on 100 patients with type II DIABETES mellitus that aged 30-70 years. The patients were randomly selected and different examinations were done on them. They received 50000 units of oral VITAMIN D daily for four weeks. INSULIN resistance was measured before and after the intervention. Data analysis was done by paired t-test and Wilcoxon test using SPSS software version 17.Results: The participants consisted of 70 women and 30 men. Mean VITAMIN D was 43.03±19.28 ng/ml and 24% of the participants were VITAMIN D deficient based on the cut-off 25 (OH) D<20 ng/ml. At the beginning and the end of the study, the mean levels for FPG, INSULIN, HOMA-IR were 138.48±36.74 and 131.02±39 mg/dl (P=0.05), 10.76±9.46 and 8.6±8.25 mIu/ml (P=0.02), and 3.57±3.18 and 2.89±3.28 (P=0.008), respectively.Conclusion: The findings of this study showed that VITAMIN D causes significant improvements in FPG, INSULIN, and INSULIN resistance, that was evaluated by HOMA-IR. It was also indicated that adding VITAMIN D supplements can improve GLUCOSE control in type II DIABETES mellitus.

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APA: Copy

TALAEI, A., MOHAMMADI, K.M., & ADGI, Z.. (2011). THE EVALUATION OF THE EFFECT OF VITAMIN D ON INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 14(5 (58)), 79-84. SID. https://sid.ir/paper/367019/en

Vancouver: Copy

TALAEI A., MOHAMMADI K.M., ADGI Z.. THE EVALUATION OF THE EFFECT OF VITAMIN D ON INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2011;14(5 (58)):79-84. Available from: https://sid.ir/paper/367019/en

IEEE: Copy

A. TALAEI, K.M. MOHAMMADI, and Z. ADGI, “THE EVALUATION OF THE EFFECT OF VITAMIN D ON INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 14, no. 5 (58), pp. 79–84, 2011, [Online]. Available: https://sid.ir/paper/367019/en

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