COMPARISON OF THREE METHODS OF URINE SAMPLING FOR SCREENING OF ALBUMINURIA IN DIABETIC PATIENTS USING IMMUNOTURBIDOMETRIC ASSAY

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MOHAMMADIZADEH F.; OMIDFAR K.; HESHMAT RAMIN; RAHMANI M.; ARDESHIR LARIJANI MOHAMMAD BAGHER

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Journal: Iranian Journal of Diabetes and Metabolism Year:2007 | Volume:6 | Issue:3 Page(s): 219-224

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Title

COMPARISON OF THREE METHODS OF URINE SAMPLING FOR SCREENING OF ALBUMINURIA IN DIABETIC PATIENTS USING IMMUNOTURBIDOMETRIC ASSAY

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Keywords

MICROALBUMINURIAQ3

24 HOURS URINE COLLECTIONQ3

8 HOUR OVERNIGHT URINE COLLECTIONQ3

SPOT URINE SAMPLINGQ3

AGREEMENTQ3

SCREENINGQ3

Abstract

Background: Microalbominuria (MA) is early presentation of renal damage which acts as an independent factor of cardiovascular events in these patients. There are various methods for sampling and also different laboratory tests to measuring albominuria. The aim of this study was to compare of different urine collection methods for measuring albominuria using immunoturbidometry assay which has acceptable accuracy and sensitivity after HPLC (High Performance Lipid Chromathography).Methods: Forty seven diabetic patients were selected for a cross-sectional study in 2006. For all patients 24-h urine sample were collected, also an overnight urine sample (8 hour long) and spot urine sample (morning time) was provided in the next day. The level of albumin in all samples was measured via immunoturbidometry assay. Then the results of AGREEMENT coefficient were accounted and comprised with each others.Results: In this study 47 patients were selected which 46 of them was type 2 and one of them type 1 diabetic. Our results revealed significant correlation between all methods. In addition AGREEMENT coefficient (kappa) was accounted for all methods, time 24-h urine in comparison with 8 hours overnight urine, timed 24-h urine in comparison with spot urine and overnight urine samples in comparison with spot urine which were 0.876, 0.936 and 0.807 respectively.Conclusion: Regarding significant AGREEMENT for SCREENING of microalbominuria between different collecting methods, we suggest 8-h overnight or SPOT URINE SAMPLING carry out instead of 24-h urine collection.

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APA: Copy

MOHAMMADIZADEH, F., OMIDFAR, K., HESHMAT, RAMIN, RAHMANI, M., & ARDESHIR LARIJANI, MOHAMMAD BAGHER. (2007). COMPARISON OF THREE METHODS OF URINE SAMPLING FOR SCREENING OF ALBUMINURIA IN DIABETIC PATIENTS USING IMMUNOTURBIDOMETRIC ASSAY. JOURNAL OF DIABETES AND METABOLIC DISORDERS, 6(3), 219-224. SID. https://sid.ir/paper/54070/en

Vancouver: Copy

MOHAMMADIZADEH F., OMIDFAR K., HESHMAT RAMIN, RAHMANI M., ARDESHIR LARIJANI MOHAMMAD BAGHER. COMPARISON OF THREE METHODS OF URINE SAMPLING FOR SCREENING OF ALBUMINURIA IN DIABETIC PATIENTS USING IMMUNOTURBIDOMETRIC ASSAY. JOURNAL OF DIABETES AND METABOLIC DISORDERS[Internet]. 2007;6(3):219-224. Available from: https://sid.ir/paper/54070/en

IEEE: Copy

F. MOHAMMADIZADEH, K. OMIDFAR, RAMIN HESHMAT, M. RAHMANI, and MOHAMMAD BAGHER ARDESHIR LARIJANI, “COMPARISON OF THREE METHODS OF URINE SAMPLING FOR SCREENING OF ALBUMINURIA IN DIABETIC PATIENTS USING IMMUNOTURBIDOMETRIC ASSAY,” JOURNAL OF DIABETES AND METABOLIC DISORDERS, vol. 6, no. 3, pp. 219–224, 2007, [Online]. Available: https://sid.ir/paper/54070/en

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