SENSITIVITY AND SPECIFICITY OF 2% TOLUIDINE BLUE SOLUTION IN THE IDENTIFICATION OF DYSPLASTIC CHANGES IN ORAL PRECANCEROUS AND CANCEROUS LESIONS

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MOSHREF M.; EBRAHIMI B.; ESLAMI B.; RESALATPANAH M.; SHOJA SAFAAR A.

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Journal: IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY Year:2003 | Volume:14 | Issue:3-4 (30) Page(s): 8-14

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Title

SENSITIVITY AND SPECIFICITY OF 2% TOLUIDINE BLUE SOLUTION IN THE IDENTIFICATION OF DYSPLASTIC CHANGES IN ORAL PRECANCEROUS AND CANCEROUS LESIONS

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Abstract

This study aims to assess the diagnostic value of 2% toluidine blue in distinguishing dysplastic precancerous lesions and cancers of oral cavity. Thirty lesions of 26 patients were stained clinically, of which 20 absorbed the characteristic blue color. Results of histopathologic evaluation were assumed the benchmark for comparison with staining records. Only five lesions displayed absence of dysplasia in the histologic view. A total sensitivity of 76% and specificity of 80% were calculated. Due to low negative predictive value (40%) and high rate of false negative outcome (20%), the negative reports of staining are concluded unreliable.

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APA: Copy

MOSHREF, M., EBRAHIMI, B., ESLAMI, B., RESALATPANAH, M., & SHOJA SAFAAR, A.. (2003). SENSITIVITY AND SPECIFICITY OF 2% TOLUIDINE BLUE SOLUTION IN THE IDENTIFICATION OF DYSPLASTIC CHANGES IN ORAL PRECANCEROUS AND CANCEROUS LESIONS. IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, 14(3-4 (30)), 8-14. SID. https://sid.ir/paper/544304/en

Vancouver: Copy

MOSHREF M., EBRAHIMI B., ESLAMI B., RESALATPANAH M., SHOJA SAFAAR A.. SENSITIVITY AND SPECIFICITY OF 2% TOLUIDINE BLUE SOLUTION IN THE IDENTIFICATION OF DYSPLASTIC CHANGES IN ORAL PRECANCEROUS AND CANCEROUS LESIONS. IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY[Internet]. 2003;14(3-4 (30)):8-14. Available from: https://sid.ir/paper/544304/en

IEEE: Copy

M. MOSHREF, B. EBRAHIMI, B. ESLAMI, M. RESALATPANAH, and A. SHOJA SAFAAR, “SENSITIVITY AND SPECIFICITY OF 2% TOLUIDINE BLUE SOLUTION IN THE IDENTIFICATION OF DYSPLASTIC CHANGES IN ORAL PRECANCEROUS AND CANCEROUS LESIONS,” IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, vol. 14, no. 3-4 (30), pp. 8–14, 2003, [Online]. Available: https://sid.ir/paper/544304/en

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