SERUM TESTOSTERONE LEVEL STUDY IN MULTIPLE SCLEROSIS PATIENTS

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SHAFA M.A.; VAKILIAN A.R.; POUREBRAHIMI A.R.; AHMADI KOHANALI JAFAR

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Journal Paper

Paper Information

Journal: Current Journal of Neurology Year:2006 | Volume:5 | Issue:15-16 Page(s): 25-32

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Title

SERUM TESTOSTERONE LEVEL STUDY IN MULTIPLE SCLEROSIS PATIENTS

Author(s)

SHAFA M.A. | VAKILIAN A.R. | POUREBRAHIMI A.R. | AHMADI KOHANALI JAFAR | Issue Writer Certificate

Keywords

MULTIPLE SCLEROSIS

TESTOSTERONE

MALE

FEMALE

Abstract

Background: MULTIPLE SCLEROSIS (MS) is the most common demyelinating disease. Autoimmune basis have been confirmed for the pathogenesis. TESTOSTERONE (TES) has the role in these immune mechanisms. Its serum level in MS had significant changes in other reports. The purpose of this study is to survey these changes in patients.Materials & Methods: In this cross sectional study 50 MS patients were selected for TES study. The same number of controls with sex and age matching were studied. Special diseases and drug users were excluded from our study. RIA was used for serum level determination of hormones.Results: In TES level survey, MALE patients had lower level of TES than controls significantly (3.01±1.45ng/ml versus 5.59±1.28ng/ml, P value< 0.0001). TES level FEMALE patents' had not significant changes. Conclusion: According to studied changes an hormone, TES have negative relation with MS in MALE patients. Further study for determination of causality relation and drug effect in endocrine system in MS pathogenesis are suggested.

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APA: Copy

SHAFA, M.A., VAKILIAN, A.R., POUREBRAHIMI, A.R., & AHMADI KOHANALI, JAFAR. (2006). SERUM TESTOSTERONE LEVEL STUDY IN MULTIPLE SCLEROSIS PATIENTS. CURRENT JOURNAL OF NEUROLOGY (IRANIAN JOURNAL OF NEUROLOGY), 5(15-16), 25-32. SID. https://sid.ir/paper/545307/en

Vancouver: Copy

SHAFA M.A., VAKILIAN A.R., POUREBRAHIMI A.R., AHMADI KOHANALI JAFAR. SERUM TESTOSTERONE LEVEL STUDY IN MULTIPLE SCLEROSIS PATIENTS. CURRENT JOURNAL OF NEUROLOGY (IRANIAN JOURNAL OF NEUROLOGY)[Internet]. 2006;5(15-16):25-32. Available from: https://sid.ir/paper/545307/en

IEEE: Copy

M.A. SHAFA, A.R. VAKILIAN, A.R. POUREBRAHIMI, and JAFAR AHMADI KOHANALI, “SERUM TESTOSTERONE LEVEL STUDY IN MULTIPLE SCLEROSIS PATIENTS,” CURRENT JOURNAL OF NEUROLOGY (IRANIAN JOURNAL OF NEUROLOGY), vol. 5, no. 15-16, pp. 25–32, 2006, [Online]. Available: https://sid.ir/paper/545307/en

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