MIXED FUNCTION OXIDASES AND INSECTICIDE RESISTANCE IN MEDICALLY IMPORTANT INSECTS

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ENAYATI A.A.; LADONI H.

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Journal Paper

Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2006 | Volume:16 | Issue:50 Page(s): 139-151

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Information Journal Paper

Title

MIXED FUNCTION OXIDASES AND INSECTICIDE RESISTANCE IN MEDICALLY IMPORTANT INSECTS

Author(s)

ENAYATI A.A. | LADONI H. | Issue Writer Certificate

Keywords

OXIDASES

INSECTICIDES

RESISTANCE

VECTORS

Abstract

MFOs are a large diverse superfamily of enzymes found in all insect tissues. They are involved in the metabolism of xenobiotics (e.g. drugs, pesticides and plant toxins) and endogenous compounds (e.g. ecdysteroids and juvenile hormones). They are also involved in bioactivation of phosphorothioate compounds such as organophosphorus INSECTICIDES. They have very diverse activities like hydroxylation, epoxidation, N-, O-or S-dealkylation, deamination, sulfoxidation, desulfuration and oxidative dehalogenation. Their diverse functions are achieved through diversity in structure. There are over 100 P450 genes in the Drosophila genome, usually arranged in family clusters. MFO-mediated insecticide metabolism is a common mechanism by which insects become resistant to INSECTICIDES. In this mini review article the role of OXIDASES in insecticide RESISTANCE is briefly discussed.

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APA: Copy

ENAYATI, A.A., & LADONI, H.. (2006). MIXED FUNCTION OXIDASES AND INSECTICIDE RESISTANCE IN MEDICALLY IMPORTANT INSECTS . JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 16(50), 139-151. SID. https://sid.ir/paper/545844/en

Vancouver: Copy

ENAYATI A.A., LADONI H.. MIXED FUNCTION OXIDASES AND INSECTICIDE RESISTANCE IN MEDICALLY IMPORTANT INSECTS . JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2006;16(50):139-151. Available from: https://sid.ir/paper/545844/en

IEEE: Copy

A.A. ENAYATI, and H. LADONI, “MIXED FUNCTION OXIDASES AND INSECTICIDE RESISTANCE IN MEDICALLY IMPORTANT INSECTS ,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 50, pp. 139–151, 2006, [Online]. Available: https://sid.ir/paper/545844/en

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