DETECTION OF EPSTEIN BARR VIRUS DNA IN THYMIC EPITHELIAL TUMOR USING NESTED PCR

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MOHAMMADI FOROUZAN; NAJI S.A.R.; KARIMI SHIRIN; MANSOURI S.D.; SHARIF KASHANI S.; BAHADORI MOSLEM

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Journal Paper

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Journal: TANAFFOS Year:2006 | Volume:5 | Issue:4 (20) Page(s): 9-13

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Title

DETECTION OF EPSTEIN BARR VIRUS DNA IN THYMIC EPITHELIAL TUMOR USING NESTED PCR

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Keywords

EPSTEIN BARR VIRUS

THYMICEPITHELIAL TUMOR

NESTED PCR

Abstract

Background: Thymus is a Iymphoepithelial organ composed of epithelial cells and Iymphocytes. Primary tumors of the thymus are uncommon and a definite risk factor has not been found. There are some reports regarding the association of the (EBV) EPSTEIN BARR VIRUS with thymic epithelial tumors. This study was conducted to evaluate the presence of EBV genome in thymic epithelial tumor.Materials and Methods: EBV genome, EBNA2 was examined from DNA extracts of 41 paraffin embedded specimens in Cluding 16 thymic epithelial tumors as subject cases and 25 mediastinal lymph nodes as controls.Results: NESTED PCR assay revealed that 31.25% of cases were positive for EBV genome.Conclusion: The presence of EBV genome EBNA2in thymic epithelial tumor suggesting that this association may be due to the endemic nature of EBV infection.

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APA: Copy

MOHAMMADI, FOROUZAN, NAJI, S.A.R., KARIMI, SHIRIN, SHARIF KASHANI, S., BAHADORI, MOSLEM, & MANSOURI, S.D.. (2006). DETECTION OF EPSTEIN BARR VIRUS DNA IN THYMIC EPITHELIAL TUMOR USING NESTED PCR. TANAFFOS, 5(4 (20)), 9-13. SID. https://sid.ir/paper/548802/en

Vancouver: Copy

MOHAMMADI FOROUZAN, NAJI S.A.R., KARIMI SHIRIN, SHARIF KASHANI S., BAHADORI MOSLEM, MANSOURI S.D.. DETECTION OF EPSTEIN BARR VIRUS DNA IN THYMIC EPITHELIAL TUMOR USING NESTED PCR. TANAFFOS[Internet]. 2006;5(4 (20)):9-13. Available from: https://sid.ir/paper/548802/en

IEEE: Copy

FOROUZAN MOHAMMADI, S.A.R. NAJI, SHIRIN KARIMI, S. SHARIF KASHANI, MOSLEM BAHADORI, and S.D. MANSOURI, “DETECTION OF EPSTEIN BARR VIRUS DNA IN THYMIC EPITHELIAL TUMOR USING NESTED PCR,” TANAFFOS, vol. 5, no. 4 (20), pp. 9–13, 2006, [Online]. Available: https://sid.ir/paper/548802/en

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