EFFECTS OF EPIGALLOCATECHIN GALLATE ON TISSUE LIPID PEROXIDE LEVELS IN TRAUMATIZED SPINAL CORD OF RAT

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KHALATBARI A.R.; AHMADVAND HASAN

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Journal: Iranian Journal of Basic Medical Sciences Year:2010 | Volume:13 | Issue:4 (47) Page(s): 239-242

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Title

EFFECTS OF EPIGALLOCATECHIN GALLATE ON TISSUE LIPID PEROXIDE LEVELS IN TRAUMATIZED SPINAL CORD OF RAT

Author(s)

KHALATBARI A.R. | AHMADVAND HASAN | Issue Writer Certificate

Keywords

ANTIOXIDANTS

EPIGALLOCATECHIN GALLATE

LIPID PEROXIDES

SPINAL CORD INJURIES

Abstract

Objective(s): Recent studies revealed the neuroprotective effects of EPIGALLOCATECHIN GALLATE (EGCG) on a variety of neural injury .The purpose of this study was to determine the effects of EGCG on the tissue lipid peroxidation after spinal cord injury (SCI).Materials and Methods: Rats were randomly divided into four groups of 7 rats each as follows: sham-operated group, trauma group, and EGCG-treatment groups (50 mg/kg, i.p., immediately and 1 hr after SCI). The rats were euthanized 24 hr after injury and then, spinal cord samples were taken for determination of malodialdehyde levels, as an indicator of lipid peroxidation.Results: The results showed that MDA levels were significantly decreased in EGCG-treatment groups.Conclusion: On the basis of these findings, we propose that EGCG may be effective in protection of spinal cord tissue from injury.

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APA: Copy

KHALATBARI, A.R., & AHMADVAND, HASAN. (2010). EFFECTS OF EPIGALLOCATECHIN GALLATE ON TISSUE LIPID PEROXIDE LEVELS IN TRAUMATIZED SPINAL CORD OF RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 13(4 (47)), 239-242. SID. https://sid.ir/paper/556822/en

Vancouver: Copy

KHALATBARI A.R., AHMADVAND HASAN. EFFECTS OF EPIGALLOCATECHIN GALLATE ON TISSUE LIPID PEROXIDE LEVELS IN TRAUMATIZED SPINAL CORD OF RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2010;13(4 (47)):239-242. Available from: https://sid.ir/paper/556822/en

IEEE: Copy

A.R. KHALATBARI, and HASAN AHMADVAND, “EFFECTS OF EPIGALLOCATECHIN GALLATE ON TISSUE LIPID PEROXIDE LEVELS IN TRAUMATIZED SPINAL CORD OF RAT,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 13, no. 4 (47), pp. 239–242, 2010, [Online]. Available: https://sid.ir/paper/556822/en

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